Results 131 to 140 of about 2,068,781 (331)

The National Image of the World in an Objective Process of Globalization [PDF]

open access: yes
The article examines process of globalization as continuation of process the creation of Christendom. The author thinks that translations of Bible from Greek or ancient Jewish on other languages are the example of first step in unification Christendom ...
Irina Shchukina
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Some linguistic remarks regarding Romanian Viking Studies [PDF]

open access: yesRevista Română pentru Studii Baltice şi Nordice, 2013
In Romania there is no academic program dedicated entirely to the study of the Viking period in Scandinavia and Europe, but Romanian historiography can still boast with a decent number of monographs, translations and studies relating to early medieval ...
Costel Coroban
doaj  

Identifying Word Translations in Non-Parallel Texts

open access: yes, 1995
Common algorithms for sentence and word-alignment allow the automatic identification of word translations from parallel texts. This study suggests that the identification of word translations should also be possible with non-parallel and even unrelated ...
Rapp, Reinhard
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

"De arauigo en lenguaie castellano": Politica linguistica e traduzione secondo Alfonso X

open access: yesLingue e Linguaggi, 2015
– After Alfonso X’s accession to the throne in mid-13th-century Spain, the translating activity of scientific texts from Arabic changed route: Castilian, instead of Latin, became the language of science.
Ruggiero Pergola
doaj  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

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