Results 101 to 110 of about 7,856,715 (298)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Arts education : validation draft

, 2000
Arts Education - Validation Draft February ...
Atlantic Provinces Education Foundation
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Preface

, 2019
This preface introduces the second edition of the volume, Towards Authentic Experiential Learning in Translator Education, an updated and expanded compendium of reports and reflections on the development and application of principles and practices for ...
Kiraly, Don, Massey, Gary
core   +2 more sources

Perbandingan terjemahan bing translator dan google translate pada teks berita aljazeera.net

, 2023
Penelitian ini bertujuan untuk menganalisis dan membandingkan hasil terjemahan Bing Translator dan Google Translate kemudian menghadirkan terjemahan yang relevan dengan menggunakan metode penerjemahan bebas.
Muhamad iqbal jabal lutfi
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Agency, Competence and GenAI in Translation and Translator Education

Acta Universitatis Carolinae Philologica
As the age of neural machine translation (NMT) has matured, agency seems to have emerged as a fulcrum around which the value of professional human translation can be judged.
Gary Massey
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Discussion, cooperation and collaboration: group learning in an online translation classroom [PDF]

, 2007
The study is an empirical investigation into the implementation of a variety of grouplearning structures in an online translation classroom. Drawing on the academic literature in the fields of translation didactics, social constructivism and e-learning ...
Kenny, Mary Ann
core   +1 more source

Professional Identity Construction of Novice Translator Trainers in Iran: An Ecological Study

Mutatis Mutandis
Teacher professional identity, understood as the ways in which teachers perceive themselves as teachers, their professional roles and practices, has received enough scholarly attention in education.
Saeed Ameri
doaj   +1 more source