Results 81 to 90 of about 17,160 (266)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Agency, Competence and GenAI in Translation and Translator Education
Acta Universitatis Carolinae PhilologicaAs the age of neural machine translation (NMT) has matured, agency seems to have emerged as a fulcrum around which the value of professional human translation can be judged.
Gary Massey
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Professional Identity Construction of Novice Translator Trainers in Iran: An Ecological Study
Mutatis MutandisTeacher professional identity, understood as the ways in which teachers perceive themselves as teachers, their professional roles and practices, has received enough scholarly attention in education.
Saeed Ameri
doaj +1 more source
‘A prompt box’: The profile of Polish official audiovisual translators
Crossroads, 2023 As audiovisual productions are becoming increasingly popular, the need for specialized translators in this field is growing. This study aims to create a profile of a typical Polish audiovisual translator who officially delivers commissioned renditions ...
Michał Organ
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
MODELING OF QUALITY IMPROVEMENT FACULTY MEMBERS IN EDUCATIONAL ORGANIZATIONS HIGHER EDUCATION
Модернизация, инновация, развитие, 2015 The transition to a two-tier system of education, the introduction of the federal state educational standards of higher education, the requirements of the single European educational space are fundamentally changing the role of faculty in the ...
N. V. Sergeeva
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source