Results 111 to 120 of about 513,979 (295)
A recurrent translocation is mediated by homologous recombination between HERV-H elements
Background Chromosome rearrangements are caused by many mutational mechanisms; of these, recurrent rearrangements can be particularly informative for teasing apart DNA sequence-specific factors.
Hermetz Karen E+3 more
doaj +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Plant Hormones Differentially Control the Sub-Cellular Localization of Plasma Membrane Microdomains during the Early Stage of Soybean Nodulation [PDF]
Phytohormones regulate the mutualistic symbiotic interaction between legumes and rhizobia, nitrogen-fixing soil bacteria, notably by controlling the formation of the infection thread in the root hair (RH).
Libault, Marc+2 more
core +1 more source
Plasmodesmos são canais responsáveis pela conexão citoplasmática entre células vizinhas, possibilitando a troca de moléculas de informação, funcionais, estruturais ou ainda de xenobióticos entre as células pertencentes a um mesmo grupo.
G. Concenço+3 more
doaj +1 more source
Genomic Comparison of Translocating and Non-Translocating Escherichia coli
Translocation of E. coli across the gut epithelium can result in fatal sepsis in post-surgical patients. In vitro and in vivo experiments have identified the existence of a novel pathotype of translocating E. coli (TEC) that employs an unknown mechanism for translocating across epithelial cells to the mesenteric lymph nodes and the blood stream in both
Bachmann, Nathan+2 more
openaire +6 more sources
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
The studies aimed to compare bioaccumulation and translocation of macronutrients from roots to above-ground organs for six species of herbaceous plants (Taraxacum officinale, Rumex acetosa L., Plantago major L., Plantago lanceolata, Potentilla anserina L.
Jerzy Jonczak, Agnieszka Parzych
doaj +1 more source
Movement in ribosome translocation.
Translocation of peptidyl-tRNA and mRNA within the ribosome during protein synthesis is promoted by the elongation factor EF-G and by the hydrolysis of GTP. A new study reports that EF-G binds to ribosomes as an EF-G.GDP complex and that GTP is exchanged for GDP on the ribosome.
Fraser, Christopher S, Hershey, John WB
openaire +5 more sources
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef+10 more
wiley +1 more source