Results 151 to 160 of about 698,201 (312)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Editorial: Metal Transport in Plants

Frontiers in Plant Science, 2021
Stephan Clemens, Seckin Eroglu, Louis Grillet, Tomoko Nozoye, Tomoko Nozoye   +4 more
doaj   +1 more source

Identification of De Novo Chromosomal Translocations Disrupting NIPBL in a Patient With Cornelia de Lange Syndrome by Full Genome Analysis

Molecular Genetics & Genomic Medicine
Background Cornelia de Lange syndrome (CdLS) is a rare genetic disorder characterized by congenital multiple anomalies, developmental delay, and distinctive facial features.
Hsiao‐Jung Kao, Elin H. F. Wang, Erh‐Chan Yeh, Hsiao‐Huei Chen, Feng‐Jen Hsieh, Tsang‐Ming Ko, Wuh‐Liang Hwu, Pui‐Yan Kwok, Ni‐Chung Lee   +8 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Translocation of diquat in the tuliptree (Liriodendron tulipifera, L.)

, 1974
Foliar application of the phytotoxic herbicide diquat dibromide was made to twenty tuliptree seedlings actively growing under field conditions on October 6, 1973, at the Purdue Davis farm in Randolph County, Indiana.
Sproat, James M.
core  

Rescue and Translocation of Hispaniola Hutia (Plagiodontia aedium) in Pueblo Viejo, Cotuí Mining Concession Area

Ecology and Evolution
Translocation of species is a common practice used in endangered species management and conservation plans, which can have the purpose of establishing new populations which are at risk of being wiped out, increase a species chance of survival or recovery,
Miguel S. Núñez‐Novas, Rosanna Carreras‐De León, Amelia L. Mateo Jiménez, Carolina Dávila, Pilar Calderón   +4 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Diverged Populations Admixture Bolsters Genetic Diversity of a New Island Dibbler (Parantechinus apicalis) Population, but Does Not Prevent Subsequent Loss of Genetic Variation

Evolutionary Applications
Translocating individuals from multiple source populations is one way to bolster genetic variation and avoid inbreeding in newly established populations.
Rujiporn Thavornkanlapachai, Harriet R. Mills, Kym Ottewell, Cathy Lambert, J. Anthony Friend, Daniel J. White, Zahra Aisya, W. Jason Kennington   +7 more
doaj   +1 more source

Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia [PDF]

, 2001
Chronic myeloid leukemia (CML) is characterized by formation of the BCR-ABL fusion gene, usually as a consequence of the Philadelphia (Ph) translocation between chromosomes 9 and 22.
Reid, AG, Campbell, LJ, Telford, N, Grace, C, Nacheva, EP, Shepherd, P, Szer, J, Green, AR, Bench, AJ, Prince, HM, Huntly, BJP, Turner, P   +11 more
core