Results 181 to 190 of about 1,020,829 (348)

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Exofacial Epitope-Specific Antibodies Detect GLUT4 Translocation in Adult Human, Rat, and Mouse Skeletal Muscle. [PDF]

Diabetes
Persson KW, Fjeldsøe C, Frandsen LW, Knudsen JR, Kwak S, Wang H, Voldstedlund CT, Leandersson MR, Witczak CA, Wojtaszewski JFP, Richter EA, Cartee GD, Jensen TE.   +12 more
europepmc   +1 more source

Incidence and significance of psammoma bodies in Xp11.2 translocation renal cell carcinoma and papillary renal cell carcinoma

, 2019
Ning Liu, Feng Qu, Kang Wei, Weidong Gan, Zhen Wang, Wenyuan Zhuang, Sezim Agizamhan, Wenliang Ma, Jun Yang, Ming Chen, Linfeng Xu, Hongqian Guo, Dongmei Li   +12 more
openalex   +2 more sources

Novel t(1;2)(p36.1;q23) and t(7;19)(q32;q13.3) chromosomal translocations in ischemic fasciitis: expanding the spectrum of pseudosarcomatous lesions with clonal pathogenetic link [PDF]

, 2018
Taha Sachak, Nyla A. Heerema, Joel Mayerson, Jason E. Payne, Anil V. Parwani, O. Hans Iwenofu   +5 more
openalex   +1 more source

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

Advanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj, Francesca Giacomini, Esra Güben Kaçmaz, Tim ten Brink, Lorenzo Moroni, Zeinab Tahmasebi Birgani, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Jan de Boer, Roman Truckenmüller   +10 more
wiley   +1 more source

Aerobactin is a key driver of hypervirulent Klebsiella pneumoniae translocation and virulence. [PDF]

PLoS Pathog
Hernandez GE, Valencia-Bacca JD, Bennett EF, Islam MM, Maiti S, Nutter NA, Young TM, Caudell DL, Costa-Terryll A, Skelly JJ, Floyd ET, Atkins HM, Zafar MA.   +12 more
europepmc   +1 more source

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

DNA-PKcs inhibitor AZD7648 reveals sgRNA cross-contaminants and enhanced sensitivity of genome engineering off-target activity in HSPCs. [PDF]

Nucleic Acids Res
White N, Hu YT, Chalk JA, Kurgan G, Naseem A, Schmaljohn E, Sturgeon M, Cavazza A, Thrasher AJ, Turchiano G.   +9 more
europepmc   +1 more source

Reviewer #1 (Public Review): Rapid translocation of NGR proteins drives polarization of PIN-activating D6 protein kinase during root gravitropism

Ivan Kulich, Júlia Schmid, Anastasia Teplova, Linlin Qi, Jiřı́ Friml   +4 more
openalex   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source