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Translocation-Related Sarcomas
Seminars in Oncology, 2009Sarcomas with chromosomal translocations represent only about one fourth of sarcoma diagnoses. However, like gastrointestinal stromal tumor (GIST), with its characteristic KIT or PDGFRA mutations, they are particularly interesting since they provide specific biological insights and mechanisms of action that may have an impact upon prognosis or therapy.
Mertens F +8 more
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Thermodynamics of the Protein Translocation
2009Many proteins synthesized in bacteria are secreted from the cytoplasm into the periplasm to function in the cell envelope or in the extracellular medium. The Sec translocase is a primary and evolutionary conserved secretion pathway in bacteria. It catalyzes the translocation of unfolded proteins across the cytoplasmic membrane via the pore-forming ...
Kedrov, A. +2 more
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Structural basis of early translocation events on the ribosome
Nature, 2021Alexander G Myasnikov +2 more
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Lung cancer: New biological insights and recent therapeutic advances
Ca-A Cancer Journal for Clinicians, 2011Suresh S Ramalingam +2 more
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Controlling protein translocation through nanopores with bio-inspired fluid walls
Nature Nanotechnology, 2011Erik C Yusko +2 more
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Retro-translocation of proteins from the endoplasmic reticulum into the cytosol
Nature Reviews Molecular Cell Biology, 2002Billy Tsai, Yihong Ye
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