Results 81 to 90 of about 1,015,611 (339)

Controlling Polymer Capture and Translocation by Electrostatic Polymer-Pore Interactions [PDF]

, 2017
Polymer translocation experiments typically involve anionic polyelectrolytes such as DNA molecules driven through negatively charged nanopores. Quantitative modelling of polymer capture to the nanopore followed by translocation therefore necessitates the
Abramowitz M., Risken H., Rowghanian P., Sahin Buyukdagli, T. Ala-Nissila   +4 more
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Predation impedes recovery of Sierra Nevada bighorn sheep

California Fish and Wildlife Journal, 2021
Translocation of animals into formerly occupied habitat is a key element of the recovery plan for Sierra Nevada bighorn sheep (Ovis canadensis sierrae), which are state (California) and federally listed as endangered. However, implementing Sierra bighorn
Daniel J. Gammons, Jeffrey L. Davis, David W. German, Kristin Denryter, John D. Wehausen, Thomas R. Stephenson   +5 more
doaj   +1 more source

Translocation of structured polynucleotides through nanopores

, 2004
We investigate theoretically the translocation of structured RNA/DNA molecules through narrow pores which allow single but not double strands to pass. The unzipping of basepaired regions within the molecules presents significant kinetic barriers for the ...
Akeson M, Bates M, Cate J H, Cech T R, Chuang J, Flomenbom O, Gerland U, Gerland U, Gutell R R, Hofacker I L, Karlin S, Koch S J, Lubensky D K, McCaskill J S, Meller A, Metzler R, Ralf Bundschuh, Terence Hwa, Ulrich Gerland, Walter A E, Zuker M   +20 more
core   +1 more source

Proton translocation in proteins [PDF]

, 1989
The active transport of protons across the low dielectric barrier imposed by biological membranes is accomplished by a plethora of proteins that span the ca. 40 Å of the phospholipid bilayer.
Chan, Sunney I., Copeland, Robert A.
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

11C-PET imaging reveals transport dynamics and sectorial plasticity of oak phloem after girdling

Frontiers in Plant Science, 2013
Carbon transport processes in plants can be followed non-invasively by repeated application of the short-lived positron-emitting radioisotope 11C, a technique which has rarely been used with trees. Recently, positron emission tomography (PET) allowing 3D
Veerle eDe Schepper, Jonas eBühler, Michael eThorpe, Michael eThorpe, Michael eThorpe, Gerhard eRoeb, Gregor eHuber, Dagmar evan Dusschoten, Siegfried eJahnke, Kathy eSteppe   +9 more
doaj   +1 more source

Anomalous Dynamics of Translocation

, 2001
We study the dynamics of the passage of a polymer through a membrane pore (translocation), focusing on the scaling properties with the number of monomers $N$. The natural coordinate for translocation is the number of monomers on one side of the hole at a
A. Baumgärtner, A. Baumgärtner, A. Meller, D. A. Hoagland, D. K. Lubensky, E. Arvanitidou, E. Ben-Naim, G. S. Grest, G. W. Slater, H. A. Kramers, I. Carmesin, I. Carmesin, I. Szabo, J. Han, Jeffrey Chuang, K. Kremer, K. L. Sebastian, M. Muthukumar, M. Muthukumar, M. Muthukumar, Mehran Kardar, N. A. Rotstein, P. G. de Gennes, P. J. Park, P. J. Park, P. Mayer, S. Chandrasekhar, S. E. Henrickson, W. Sung, Yacov Kantor   +29 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Integrative biochar and melatonin application mitigates lead toxicity in rice by modulating antioxidant activities and iron plaque formation and downregulating the expression of metal uptake genes

Frontiers in Plant Science
Lead (Pb) is a common toxic metal that causes severe health and environmental problems. However, the defensive role and underlying mechanism of combined biochar (BC) and melatonin (MT) against Pb stress are still unclear.
Tahir Abbas Khan, Qitao Su, Huang Guoqin, Zhixuan Du, Zhixuan Du, Mehmood Ali Noor, Tahani A. Y. Asseri, Muhammad Umair Hassan   +7 more
doaj   +1 more source