Results 21 to 30 of about 19,113 (196)
The porcine microRNA transcriptome response to transmissible gastroenteritis virus infection. [PDF]
Transmissible gastroenteritis virus (TGEV; Coronaviridae family) causes huge economic losses to the swine industry. MicroRNAs (miRNAs) play a regulatory role in viral infection and may be involved in the mammalian immune response.
Xiao Liu +4 more
doaj +1 more source
Autophagy Negatively Regulates Transmissible Gastroenteritis Virus Replication [PDF]
AbstractAutophagy is an evolutionarily ancient pathway that has been shown to be important in the innate immune defense against several viruses. However, little is known about the regulatory role of autophagy in transmissible gastroenteritis virus (TGEV) replication. In this study, we found that TGEV infection increased the number of autophagosome-like
Longjun Guo +10 more
openaire +2 more sources
Physicochemical properties of transmissible gastroenteritis virus hemagglutinin [PDF]
Transmissible gastroenteritis virus was readily adsorbed onto chicken erythrocytes at 4 degrees C. The hemagglutinin thus adsorbed could be eluted from the erythrocytes by incubating in phosphate buffered saline at 37 degrees C. The receptor on chicken erythrocytes for the hemagglutinin was inactivated by neuraminidase and potassium periodate, but not ...
Noda, M. +3 more
openaire +2 more sources
The dna vaccine combining the adjuvant porcine il-12 with the spike gene of transmissible gastroenteritis virus enhances the immune response in swine [PDF]
Transmissible gastroenteritis (TGE), cause by transmissible gastroenteritis virus (TGEV), is an acute digestive and highly infectious disease in piglets. In this study, porcine interleukin-12 immunological adjuvant combined with a DNA vaccine bearing the
Xunliang LI +5 more
doaj +1 more source
Background. Viral infections trigger transcription factors, including Nrf2, which regulate the expression of genes related to cytokines, chemokines, and more.
Maryna Arkhypova +8 more
doaj +1 more source
Porcine innate and adaptative immune responses to influenza and coronavirus infections [PDF]
Both innate and adaptative immune responses contribute to the control of infectious diseases, including by limiting the spreading of zoonotic diseases from animal reservoirs to humans.
Asselin-Paturel +35 more
core +2 more sources
Swine enteric coronaviruses (SECs) cause significant economic losses to the pig industry in China. Although many commercialized vaccines against transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) are available, viruses ...
Fanzhi Kong +4 more
doaj +1 more source
There was performed the study of immunogenic properties of the transmissible gastroenteritis virus antigen conjugated to gold nanoparticles. In comparative immunobiological studies there was found that immunization of guinea pigs driven by the colloidal ...
Pavel V. Mezhenny +7 more
doaj +1 more source
miR-27b attenuates apoptosis induced by transmissible gastroenteritis virus (TGEV) infection via targeting runt-related transcription factor 1 (RUNX1) [PDF]
Transmissible gastroenteritis virus (TGEV), belonging to the coronaviridae family, is the key cause of the fatal diarrhea of piglets and results in many pathological processes.
Xiaomin Zhao +9 more
doaj +2 more sources
Molecular biology of transmissible gastroenteritis virus
The causative agent (TGEV) of porcine transmissible gastroenteritis belongs to the Coronaviridae, a family of enveloped viruses with a positive, single-stranded RNA genome. Important progress has recently been made concerning the molecular biology of TGEV.
Laude, Hubert +5 more
openaire +3 more sources

