Results 91 to 100 of about 1,172,761 (182)

Transmissible Gastroenteritis Virus Infection Up-Regulates FcRn Expression via Nucleocapsid Protein and Secretion of TGF-β in Porcine Intestinal Epithelial Cells

Frontiers in Microbiology, 2020
Transmissible gastroenteritis virus (TGEV) is a porcine intestinal coronavirus that causes fatal severe watery diarrhea in piglets. The neonatal Fc receptor (FcRn) is the only IgG transport receptor, its expression on mucosal surfaces is triggered upon ...
Shaoju Qian, Zitong Gao, Rui Cao, Kang Yang, Yijie Cui, Shaowen Li, Shaowen Li, Shaowen Li, Xianrong Meng, Xianrong Meng, Xianrong Meng, Qigai He, Qigai He, Qigai He, Zili Li, Zili Li, Zili Li   +16 more
doaj   +1 more source

Isolation and Characterization of a Highly Virulent Getah Virus Causing Acute Lethal Infection in Neonatal Piglets

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Getah virus (GETV) is a mosquito‐borne alphavirus with an expanding host range and an increasing impact on swine production, particularly in neonatal piglets. In this study, a severe disease outbreak characterized by acute diarrhea and high mortality occurred among suckling piglets on a commercial pig farm in central China.
Zhengxin Yang, Weidong Yan, Xuefei Wang, Mengjia Zhang, Zongyang Peng, Mengdi Zhang, Ahmed H. Ghonaim, Xuexiang Yu, Thi Trang Vy, Xugang Ku, Mingguang Zhou, Gaoyuan Xu, Anan Jongkaewwattana, Qigai He, Wentao Li, Shao-Lun Zhai   +15 more
wiley   +1 more source

Emergence of a Highly Virulent Porcine Epidemic Diarrhea Virus (PEDV) G2c Subtype in China: Isolation, Genetic and Pathogenic Characterization, and Cross‐Neutralizing Antibody Response

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Yang-Yang Li, Chuan-Hao Fan, Hai-Xia Li, Hui-Qiang Zhen, Ye-Qing Zhu, Shouyu Wang, Bin Wang, Yao-Wei Huang, Linzhu Ren   +8 more
wiley   +1 more source

Ten Years Later: Molecular Detection and Circulation of Enteric Viruses in Italian Pig Herds

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Enteric viral infections remain a major challenge for the swine industry, particularly in young animals, and represent a potential source of zoonotic risk. Ten years after a previous survey conducted in Italy, we performed a cross‐sectional study investigating mostly the same viruses to evaluate the persistence and circulation of different enteric ...
Ilaria Di Bartolo, Fabio Ostanello, Giovanni Ianiro, Luca De Sabato, Chiara Settanni, Irene Berselli, David Ranucci, Marina Monini, Fedor Korennoy   +8 more
wiley   +1 more source

Characterization of viral proteases from Norwalk virus, poliovirus, and transmissible gastroenteritis virus using a fluorescence resonance energy transfer assay [PDF]

Master of ScienceDepartment of Diagnostic Medicine/PathobiologyKyeong-Ok ChangPositive sense RNA viruses include diverse groups of viruses that cause a wide variety of diseases in humans and animals. Most of these viruses encode proteases that cleave the
Pasupulleti, Venkata Kiran
core  

Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Jialu Zhang, Yuqian Liu, Shuying Ren, Zhouyuan Wang, Yunxia Li, Lianci Peng, Rendong Fang, Jianchao Wei   +7 more
wiley   +1 more source

Essential Envelope Spike Motifs for Cell Entry of Transmissible Gastroenteritis Virus and Its Evolution in Coronavirus

Receptors
Background: Transmissible gastroenteritis virus (TGEV), a coronavirus (CoV) infecting pigs, uses its spike (S) glycoprotein to bind porcine aminopeptidase N (pAPN) for cell entry. Although structural studies have identified receptor-binding motifs (RBMs)
Gaurav Mudgal, Fernando Almazán, Tadeo Moreno-Chicano, Alberto Martínez-Colom, Cesar Santiago, Luis Enjuanes, José M. Casasnovas   +6 more
doaj   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

Impact of TGEV infection on the pig small intestine

Virology Journal, 2018
Background Pig diarrhea causes high mortality and large economic losses in the swine industry. Transmissible gastroenteritis virus (TGEV) causes pig diarrhea, with 100% mortality in piglets less than 2 weeks old. No investigation has yet been made of the
Lu Xia, Yunhan Yang, Jialu Wang, Yuchao Jing, Qian Yang   +4 more
doaj   +1 more source

Location of antigenic sites of the S-glycoprotein of transmissible gastroenteritis virus and their conservation in coronaviruses

, 1990
Transmissible gastroenteritis virus (TGEV) has a single-stranded, positive-sense RNA genome of more than 20 kb (Brian et al., 1980; Rasschaert et al., 1987) and three structural proteins: S, N and M, with 1447, 382 and 262 amino acids, respectively ...
F. Gebauer, I. Correa, C. Suñé, L. Enjuanes, Sune, C., Meloen, R. H., R. H. Meloen, Smerdou, C., Enjuanes, L., Lenstra, J. A., W. P. A. Posthumus, Correa, I., Bullido, M. J., LS IRAS Tox Algemeen, Gebauer, F., Sanchez, C., M. J. Bullido, C. Smerdou, C. Sánchez, Posthumus, W. P A, Sub ULS, J. A. Lenstra   +21 more
core   +1 more source