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Transmissible Gastroenteritis Virus (TGEV) and Porcine Respiratory Coronavirus (PRCV): Epidemiology and Molecular Characteristics—An Updated Overview

Viruses
Transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus (PRCV) are enveloped, single-stranded RNA viruses belonging to the genus Alphacoronavirus in the family Coronaviridae.
Monika Olech, Marta Antas
exaly   +4 more sources

Establishment of a Pseudovirus Neutralization Assay for TGEV

Frontiers in Immunology
IntroductionTransmissible Gastroenteritis Virus (TGEV) is a major pathogen causing swine enteric diseases, necessitating effective control strategies. Vaccination plays a key role, but assessing vaccine efficacy remains challenging due to variations in ...
Hongyan Chen, Changyou Xia, Lihong Xue
exaly   +5 more sources

Engineering a TGEV S-Trimer Chimera With PEDV D0-NTD Generates Potent Neutralizing Antibodies Against Both Viruses. [PDF]

Journal of Virology
Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV), two economically devastating swine enteric coronaviruses, persistently threaten global pork production via severe clinical morbidity. Vaccination is the most effective
Hanqin Shen, Guiqing Peng, Yuejun Shi
exaly   +4 more sources

Bioinformatic analysis of differentially expressed genes in porcine intestinal epithelial cells infected with transmissible gastroenteritis virus [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021
Transmissible Gastroenteritis Virus (TGEV) infection is one of the leading causes of diarrhea in piglets. Intestinal immune system plays an important role in maintaining the intestinal mucosa"s integrity and resisting infection by pathogens. However, the
Xu-xuan ZHANG, Guo-wei LAN, Zhe WANG, Chen-hao JIANG, Jing XI, Yao LI, Jun QIAO, Yan REN   +7 more
doaj   +1 more source

All-Trans Retinoic Acid Attenuates Transmissible Gastroenteritis Virus-Induced Inflammation in IPEC-J2 Cells via Suppressing the RLRs/NF‐κB Signaling Pathway

Frontiers in Immunology, 2022
Transmissible gastroenteritis virus (TGEV) infection can cause transmissible gastroenteritis (TGE), especially in suckling piglets, resulting in a significant economic loss for the global pig industry.
Junning Pu, Daiwen Chen, Gang Tian, Jun He, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Yuheng Luo, Hui Yan, Bing Yu   +11 more
doaj   +1 more source

Eugenol Attenuates Transmissible Gastroenteritis Virus-Induced Oxidative Stress and Apoptosis Via ROS-NRF2-ARE Signaling

Antioxidants, 2022
Transmissible gastroenteritis virus (TGEV), a coronavirus that causes severe diarrhea due to oxidative stress in the piglet intestine, is a major cause of economic loss in the livestock industry.
Kang Wang, Yan Tang, Xiu Wu, Hongmin Liang, Daiwen Chen, Bing Yu, Jun He, Xiangbing Mao, Zhiqing Huang, Hui Yan, Aimin Wu, Yuheng Luo, Ping Zheng, Jie Yu, Huifen Wang, Junqiu Luo   +15 more
doaj   +1 more source

Role of Porcine Aminopeptidase N and Sialic Acids in Porcine Coronavirus Infections in Primary Porcine Enterocytes

Viruses, 2020
Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) have been reported to use aminopeptidase N (APN) as a cellular receptor. Recently, the role of APN as a receptor for PEDV has been questioned. In our study, the role of
Tingting Cui, Sebastiaan Theuns, Jiexiong Xie, Wim Van den Broeck, Hans J. Nauwynck   +4 more
doaj   +1 more source

Transmissible Gastroenteritis Virus: An Update Review and Perspective

Viruses, 2023
Transmissible gastroenteritis virus (TGEV) is a member of the alphacoronavirus genus, which has caused huge threats and losses to pig husbandry with a 100% mortality in infected piglets.
Yiwu Chen, Yuanzhu Zhang, Xi Wang, Jian Zhou, Lerong Ma, Jianing Li, Lin Yang, Hongsheng Ouyang, Hongming Yuan, Daxin Pang   +9 more
doaj   +1 more source

Transferrin receptor 1 is a supplementary receptor that assists transmissible gastroenteritis virus entry into porcine intestinal epithelium

Cell Communication and Signaling, 2018
Background Transmissible gastroenteritis virus (TGEV), the etiologic agent of transmissible gastroenteritis, infects swine of all ages causing vomiting and diarrhea, in newborn piglets the mortality rate is near 100%.
Shuai Zhang, Weiwei Hu, Lvfeng Yuan, Qian Yang   +3 more
doaj   +1 more source

Differential Transcriptomics Analysis of IPEC-J2 Cells Single or Coinfected With Porcine Epidemic Diarrhea Virus and Transmissible Gastroenteritis Virus

Frontiers in Immunology, 2022
Porcine epidemic diarrhea (PED) and transmissible gastroenteritis (TGE) caused by porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) are two highly contagious intestinal diseases in the swine industry worldwide. Notably,
Lina Song, Lina Song, Jing Chen, Pengfei Hao, Yuhang Jiang, Wang Xu, Letian Li, Si Chen, Zihan Gao, Ningyi Jin, Linzhu Ren, Chang Li   +11 more
doaj   +1 more source