Impact of TGEV infection on the pig small intestine [PDF]
Virology Journal, 2018 Background Pig diarrhea causes high mortality and large economic losses in the swine industry. Transmissible gastroenteritis virus (TGEV) causes pig diarrhea, with 100% mortality in piglets less than 2 weeks old. No investigation has yet been made of the
Yunhan Yang, Yuchao Jing, Qian Yang
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Transmissible Gastroenteritis Virus Binding to Red Blood Cells Disrupts Iron Homeostasis and Promotes Viral Infection [PDF]
Veterinary SciencesRed blood cells (RBCs) are essential for transporting oxygen from lungs to peripheral tissues. However, the impact of transmissible gastroenteritis virus (TGEV) infection on RBCs and its potential pathophysiological significance during disease ...
Lu Xia +9 more
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Engineering a TGEV S-trimer chimera with PEDV D0-NTD generates potent neutralizing antibodies against both viruses [PDF]
Journal of VirologyPorcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV), two economically devastating swine enteric coronaviruses, persistently threaten global pork production via severe clinical morbidity. Vaccination is the most effective
Ding Zhang +11 more
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TRIM7 suppresses transmissible gastroenteritis virus replication by targeting the degradation of N protein and activating RIG-I-mediated type I IFN antiviral response [PDF]
Veterinary ResearchTransmissible gastroenteritis virus (TGEV) is a major enteric pathogen causing severe diarrhea in swine, with substantial implications for the biosecurity of intensive pig production worldwide. The E3 ubiquitin ligase TRIM7 has emerged as a key regulator
Weiyun Qin +6 more
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Screening and characterization of monoclonal antibodies with neutralizing activity against porcine transmissible gastroenteritis virus [PDF]
BMC Veterinary ResearchBackground Porcine Transmissible Gastroenteritis Virus (TGEV) is widespread and frequently involved in co-infections, leading to high mortality rates in piglets and significantly constraining the swine industry.
Hangyu Jia +7 more
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Transcriptome-Wide Identification and Analysis Reveals m6A Regulation of Porcine Intestinal Epithelial Cells Under TGEV Infection [PDF]
Veterinary SciencesTransmissible gastroenteritis virus (TGEV) represents a critical intestinal pathogen responsible for acute enteritis in pigs, posing significant challenges to global swine production biosecurity.
Ying Liu +3 more
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A novel linear B-cell epitope on S2 protein of transmissible gastroenteritis virus identified using a monoclonal antibody [PDF]
BMC Veterinary ResearchBackground Transmissible gastroenteritis virus (TGEV) is a devastating coronavirus that causes severe gastrointestinal symptoms and high mortality in piglets, resulting in substantial economic losses in the swine industry.
Jinhui Hou +11 more
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In vitro virucidal activity of chemical compounds against porcine transmissible gastroenteritis virus and porcine respiratory coronavirus [PDF]
BMC Veterinary ResearchPorcine transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus (PRCV) are enveloped, single-stranded RNA viruses belonging to the genus Alphacoronavirus in the family Coronaviridae.
Marta Antas, Monika Olech
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Bioinformatic analysis of differentially expressed genes in porcine intestinal epithelial cells infected with transmissible gastroenteritis virus [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021 Transmissible Gastroenteritis Virus (TGEV) infection is one of the leading causes of diarrhea in piglets. Intestinal immune system plays an important role in maintaining the intestinal mucosa"s integrity and resisting infection by pathogens. However, the
Xu-xuan ZHANG +7 more
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Frontiers in Immunology, 2022 Transmissible gastroenteritis virus (TGEV) infection can cause transmissible gastroenteritis (TGE), especially in suckling piglets, resulting in a significant economic loss for the global pig industry.
Junning Pu +11 more
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