Results 21 to 30 of about 14,813 (212)

Transferrin receptor 1 is a supplementary receptor that assists transmissible gastroenteritis virus entry into porcine intestinal epithelium

Cell Communication and Signaling, 2018
Background Transmissible gastroenteritis virus (TGEV), the etiologic agent of transmissible gastroenteritis, infects swine of all ages causing vomiting and diarrhea, in newborn piglets the mortality rate is near 100%.
Shuai Zhang, Weiwei Hu, Lvfeng Yuan, Qian Yang   +3 more
doaj   +1 more source

Porcine innate and adaptative immune responses to influenza and coronavirus infections [PDF]

, 2006
Both innate and adaptative immune responses contribute to the control of infectious diseases, including by limiting the spreading of zoonotic diseases from animal reservoirs to humans.
Asselin-Paturel, Baudoux, BERNARD CHARLEY, Brim, Charley, Charley, Charley, Chen, Chinsangaram, Corthier, Fitzgerald-Bocarsly, Guzylack-Piriou, Heinen, KRISTIEN VAN REETH, La Bonnardière, Laude, Laude, Le Bon, Lim, Liu, Palese, Peiris, Pestka, Riffault, Riffault, Riffault, Rothenfusser, SABINE RIFFAULT, Saif, Siegal, Summerfield, Tu, Tudor, Van Reeth, Van Reeth, van Reeth   +35 more
core   +2 more sources

Evaluation of the Serologic Cross-Reactivity between Transmissible Gastroenteritis Coronavirus and Porcine Respiratory Coronavirus Using Commercial Blocking Enzyme-Linked Immunosorbent Assay Kits

mSphere, 2019
This study compared the performances of three commercial transmissible gastroenteritis virus/porcine respiratory coronavirus (TGEV/PRCV) blocking enzyme-linked immunosorbent assays (ELISAs) using serum samples (n = 528) collected over a 49-day ...
Ronaldo Magtoto, Korakrit Poonsuk, David Baum, Jianqiang Zhang, Qi Chen, Ju Ji, Pablo Piñeyro, Jeffrey Zimmerman, Luis G. Giménez-Lirola   +8 more
doaj   +1 more source

Understanding Viral Transmission Behavior via Protein Intrinsic Disorder Prediction: Coronaviruses [PDF]

, 2012
Besides being a common threat to farm animals and poultry, coronavirus (CoV) was responsible for the human severe acute respiratory syndrome (SARS) epidemic in 2002-4. However, many aspects of CoV behavior, including modes of its transmission, are yet to
Dunker, A. Keith, Goh, Gerard Kian-Meng, Uversky, Vladmir N.   +2 more
core   +3 more sources

Prediction of Intrinsic Disorder in MERS-CoV/HCoV-EMC Supports a High Oral-Fecal Transmission [PDF]

, 2013
A novel coronavirus, MERS-CoV (NCoV, HCoV-EMC/2012), originating from the Middle-East, has been discovered. Incoming data reveal that the virus is highly virulent to humans.
Dunker, A. Keith, Goh, Gerard Kian-Meng, Uversky, Vladmir   +2 more
core   +1 more source

Induction of Antibodies Protecting against Transmissible Gastroenteritis Coronavirus (TGEV) by Recombinant Adenovirus Expressing TGEV Spike Protein

Virology, 1995
Ten recombinant adenoviruses expressing either fragments of 1135, 1587, or 3329 nt or the full-length spike gene of transmissible gastroenteritis coronavirus (TGEV) have been constructed. These recombinants produce S polypeptides with apparent molecular masses of 68, 86, 135, and 200 kDa, respectively.
TORRES, JUAN M., SÁNCHEZ, CARLOS, SUÑÉ, CARLOS, SMERDOU, CRISTIAN, PREVEC, LUDVIK, GRAHAM, FRANK, ENJUANES, LUIS   +6 more
openaire   +2 more sources

Transmissible Gastroenteritis Virus Infection Up-Regulates FcRn Expression via Nucleocapsid Protein and Secretion of TGF-β in Porcine Intestinal Epithelial Cells

Frontiers in Microbiology, 2020
Transmissible gastroenteritis virus (TGEV) is a porcine intestinal coronavirus that causes fatal severe watery diarrhea in piglets. The neonatal Fc receptor (FcRn) is the only IgG transport receptor, its expression on mucosal surfaces is triggered upon ...
Shaoju Qian, Zitong Gao, Rui Cao, Kang Yang, Yijie Cui, Shaowen Li, Shaowen Li, Shaowen Li, Xianrong Meng, Xianrong Meng, Xianrong Meng, Qigai He, Qigai He, Qigai He, Zili Li, Zili Li, Zili Li   +16 more
doaj   +1 more source

Characterization of Two Monoclonal Antibodies That Recognize Linker Region and Carboxyl Terminal Domain of Coronavirus Nucleocapsid Protein. [PDF]

PLoS ONE, 2016
The transmissible gastroenteritis virus (TGEV) nucleocapsid (N) protein plays important roles in the replication and translation of viral RNA. The present study provides the first description of two monoclonal antibodies (mAbs) (5E8 and 3D7) directed ...
Xin Zhang, Xin Zhao, Hui Dong, Yunnuan Zhu, Hongyan Shi, Jianfei Chen, Da Shi, Li Feng   +7 more
doaj   +1 more source

The essential role of mitochondrial dynamics in antiviral immunity. [PDF]

, 2018
Viruses alter cellular physiology and function to establish cellular environment conducive for viral proliferation. Viral immune evasion is an essential aspect of viral persistence and proliferation.
Ahn, Dae-Gyun, Kim, Seong-Jun, Siddiqui, Aleem, Syed, Gulam H   +3 more
core   +2 more sources

Transmissible gastroenteritis virus infection decreases arginine uptake by downregulating CAT-1 expression

Veterinary Research, 2018
Transmissible gastroenteritis virus (TGEV) is a coronavirus that causes severe diarrhea in suckling piglets. TGEV primarily targets and infects porcine intestinal epithelial cells, which play an important role in nutrient absorption. However, the effects
Lu Xia, Lei Dai, Qian Yang
doaj   +1 more source