Results 31 to 40 of about 13,537 (210)

Evaluation of the Effect of Inactivated Transmissible Gastroenteritis Virus Vaccine with Nano Silicon on the Phenotype and Function of Porcine Dendritic Cells

Viruses, 2021
A transmissible gastroenteritis virus (TGEV) is a porcine enteropathogenic coronavirus, causing acute swine enteric disease especially in suckling piglets.
Lanlan Zheng, Fujie Zhao, Jiaxi Ru, Lintao Liu, Zi Wang, Nianxiang Wang, Xiangli Shu, Zhanyong Wei, Huichen Guo   +8 more
doaj   +1 more source

In vitro and in vivo expression of foreign genes by transmissible gastroenteritis coronavirus-derived minigenomes [PDF]

, 2002
A helper-dependent expression system based on transmissible gastroenteritis coronavirus (TGEV) has been developed using a minigenome of 3·9 kb (M39).
Enjuanes, L., Plana-Duran, J., Reimann, I., Moormann, R.J.M., Sola, I., Plana Duran, J., Alonso, S., Izeta, A., Teifke, J.P., Teifke, Jens Peter, Reimann, Ilona, Balasch, M.   +11 more
core   +1 more source

Transmissible Gastroenteritis Virus Infection Up-Regulates FcRn Expression via Nucleocapsid Protein and Secretion of TGF-β in Porcine Intestinal Epithelial Cells

Frontiers in Microbiology, 2020
Transmissible gastroenteritis virus (TGEV) is a porcine intestinal coronavirus that causes fatal severe watery diarrhea in piglets. The neonatal Fc receptor (FcRn) is the only IgG transport receptor, its expression on mucosal surfaces is triggered upon ...
Shaoju Qian, Zitong Gao, Rui Cao, Kang Yang, Yijie Cui, Shaowen Li, Shaowen Li, Shaowen Li, Xianrong Meng, Xianrong Meng, Xianrong Meng, Qigai He, Qigai He, Qigai He, Zili Li, Zili Li, Zili Li   +16 more
doaj   +1 more source

Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway

Frontiers in Immunology, 2022
Increasing evidence supports the ability of eugenol to maintain intestinal barrier integrity and anti-inflammatory in vitro and in vivo; however, whether eugenol alleviates virus-mediated intestinal barrier damage and inflammation remains a mystery ...
Kang Wang, Kang Wang, Daiwen Chen, Daiwen Chen, Bing Yu, Bing Yu, Jun He, Jun He, Xiangbing Mao, Xiangbing Mao, Zhiqing Huang, Zhiqing Huang, Hui Yan, Hui Yan, Aimin Wu, Aimin Wu, Yuheng Luo, Yuheng Luo, Ping Zheng, Ping Zheng, Jie Yu, Jie Yu, Junqiu Luo, Junqiu Luo   +23 more
doaj   +1 more source

The N-Terminal Domain of Spike Protein Is Not the Enteric Tropism Determinant for Transmissible Gastroenteritis Virus in Piglets

Viruses, 2019
Transmissible gastroenteritis virus (TGEV) is the etiologic agent of transmissible gastroenteritis in pigs, and the N-terminal domain of TGEV spike protein is generally recognized as both the virulence determinant and enteric tropism determinant.
Gang Wang, Rui Liang, Ziwei Liu, Zhou Shen, Jiale Shi, Yuejun Shi, Feng Deng, Shaobo Xiao, Zhen F. Fu, Guiqing Peng   +9 more
doaj   +1 more source

Cloning and expression of nucleocapsid protein gene of TGEV HB06 strain [PDF]

Frontiers of Agriculture in China, 2007
The nucleocapsid protein gene of transmissible gastroenteritis virus, 1 149 bp in length, was amplified by RT-PCR from isolated strain HB06 and cloned into pMD18-T. Sequence comparison with other transmissible gastroenteritis virus (TGEV) strains selected from the Gene Bank revealed that the homology of N gene complete sequence shares more than 97% in ...
Fan, Jinghui, Zuo, Yuzhu, Zhao, Yuelan, Li, Tanqing, Zhang, Xiaobo   +4 more
openaire   +2 more sources

Transmissible gastroenteritis virus infection decreases arginine uptake by downregulating CAT-1 expression

Veterinary Research, 2018
Transmissible gastroenteritis virus (TGEV) is a coronavirus that causes severe diarrhea in suckling piglets. TGEV primarily targets and infects porcine intestinal epithelial cells, which play an important role in nutrient absorption. However, the effects
Lu Xia, Lei Dai, Qian Yang
doaj   +1 more source

Characterization of Two Monoclonal Antibodies That Recognize Linker Region and Carboxyl Terminal Domain of Coronavirus Nucleocapsid Protein. [PDF]

PLoS ONE, 2016
The transmissible gastroenteritis virus (TGEV) nucleocapsid (N) protein plays important roles in the replication and translation of viral RNA. The present study provides the first description of two monoclonal antibodies (mAbs) (5E8 and 3D7) directed ...
Xin Zhang, Xin Zhao, Hui Dong, Yunnuan Zhu, Hongyan Shi, Jianfei Chen, Da Shi, Li Feng   +7 more
doaj   +1 more source

The Viral Nucleocapsid Protein of Transmissible Gastroenteritis Coronavirus (TGEV) Is Cleaved by Caspase-6 and -7 during TGEV-Induced Apoptosis

Journal of Virology, 2000
ABSTRACT The transmissible gastroenteritis coronavirus (TGEV), like many other viruses, exerts much of its cytopathic effect through the induction of apoptosis of its host cell. Apoptosis is coordinated by a family of cysteine proteases, called caspases, that are activated during apoptosis and participate in dismantling the cell ...
Eléouët, Jean-François, Slee, E.A., Saurini, F., Castagné, N., Poncet, Didier, Garrido, Carmen, Solary, E., Martin, S.J.   +7 more
openaire   +4 more sources

Evaluation on the efficacy and immunogenicity of recombinant DNA plasmids expressing spike genes from porcine transmissible gastroenteritis virus and porcine epidemic diarrhea virus. [PDF]

PLoS ONE, 2013
Porcine transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PDEV) can cause severe diarrhea in pigs. Development of effective vaccines against TGEV and PEDV is one of important prevention measures. The spike (S) protein is the
Fandan Meng, Yudong Ren, Siqingaowa Suo, Xuejiao Sun, Xunliang Li, Pengchong Li, Wei Yang, Guangxing Li, Lu Li, Christel Schwegmann-Wessels, Georg Herrler, Xiaofeng Ren   +11 more
doaj   +1 more source