Results 61 to 70 of about 889,883 (299)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Measuring the Long-Term Uncertainty Effect Reduction on Transmission Expansion Planning [PDF]

International Journal of Mathematical, Engineering and Management Sciences
Transmission expansion planning (TEP) is known as long-term study, which is related to the generation expansion pattern, i.e. where and how many new generation facilities will be constructed.
Payam Dalaliyan Miandoab, Peyman Nazarian, Majid Moradlou   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Input-output description of microwave radiation in the dynamical Coulomb blockade [PDF]

, 2014
We study microwave radiation emitted by a small voltage-biased Josephson junction connected to a superconducting transmission line. An input-output formalism for the radiation field is established, using a perturbation expansion in the junction's ...
Fogelström, Mikael, Johansson, Göran, Leppäkangas, Juha, Marthaler, Michael   +3 more
core   +3 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Comprehensive Analysis of Approaches for Transmission Network Expansion Planning

IEEE Access
Research has been conducted on transmission network expansion planning (TNEP) in recent years. TNEP is an essential component of power network planning that identifies the specific locations, timing, and quantity of additional transmission lines to be ...
Nomihla Wandile Ndlela, Katleho Moloi, Musasa Kabeya   +2 more
doaj   +1 more source

Optimum HVAC-transmission expansion planning

International Journal of Electrical Power & Energy Systems, 1987
Abstract A new, flexible, mixed-integer formulation is presented for solving the single-stage AC-transmission expansion planning problem. This new formulation handles the discrete nature of equipment additions without resorting to linearized incremental approaches, but still uses integer linear programming.
M.L. Gilles, J. Meisel
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Decentralized Solution for Transmission Expansion Planning: Getting Inspiration from Nature

Energies, 2019
Transmission expansion planning is a problem of considerable complexity where classical optimization techniques are unable to handle large case studies. Decomposition and divide-and-conquer strategies have been applied to this problem.
Sara Lumbreras, Sonja Wogrin, Guillermo Navarro, Ilaria Bertazzi, Maria Pereda   +4 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source