Results 61 to 70 of about 1,701,551 (356)

Death after Kidney Transplantation: An Analysis by Era and Time Post-Transplant.

Journal of the American Society of Nephrology, 2020
BACKGROUND Mortality risk after kidney transplantation can vary significantly during the post-transplant course. A contemporary assessment of trends in all-cause and cause-specific mortality at different periods post-transplant is required to better ...
Tracey Ying, Bree Shi, P. Kelly, H. Pilmore, P. Clayton, S. Chadban   +5 more
semanticscholar   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Impact of Infection on Transplant Outcomes: Transplant Infectious Disease Expertise as an Essential Component of Transplant Programs

, 2021
Infectious complications are a major cause of morbidity and mortality in both solid organ and hematopoietic stem cell transplant patients. The risk of infection by common opportunistic pathogens like cytomegalovirus can be mitigated with the optimal use ...
Morris, Michele I., Wolfe, Cameron R.
core   +1 more source

Elevated procalcitonin level in early postoperative period after liver transplantation is not an indicator for systemic infection - a case report

Indian Journal of Transplantation, 2020
Elevated procalcitonin (Pct) in the early postoperative phase after liver transplantation often may present a diagnostic dilemma. We report a 40-year-old patient after deceased donor liver transplant who had elevated Pct on postoperative day (POD) 2 ...
Hirak Pahari, Nikhil Shellagi, Barun Nath   +2 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Incidence, Risk Factors and Outcomes of Urinary Tract Infections in Renal Transplant Recipients – Prospective Observational Study

Indian Journal of Transplantation
Introduction: Urinary tract infections (UTI) are the most common infections following kidney transplantation. Risk factors for posttransplant UTI include female gender, advanced recipient age, pretransplant bladder abnormalities and posttransplant ...
Jasmine Sethi, Shivakumar Patil, Suvarna Raju Chinege, Balwinder Mohan, Sarabpreet Singh, Manish Rathi, Deepesh Benjamin Kenwar, Ashish Sharma   +7 more
doaj   +1 more source

Effect of Tandem Autologous Stem Cell Transplant vs Single Transplant on Event-Free Survival in Patients With High-Risk Neuroblastoma: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Induction chemotherapy followed by high-dose therapy with autologous stem cell transplant and subsequent antidisialoganglioside antibody immunotherapy is standard of care for patients with high-risk neuroblastoma, but survival rate among these
Julie R. Park, S. Kreissman, W. London, A. Naranjo, S. Cohn, M. Hogarty, Sheena C. Tenney, D. Haas-Kogan, P. Shaw, J. Kraveka, S. Roberts, J. Geiger, J. Doski, S. Voss, J. Maris, S. Grupp, L. Diller   +16 more
semanticscholar   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Individualized immunosuppression in transplant patients: potential role of pharmacogenetics.

, 2012
The immunosuppressive drugs used to prevent the rejection of transplanted organs have a narrow therapeutic index. Under treatment results in episodes of rejection leading to either damage or loss of the organ. Over immunosuppression increases the risk of
MacPhee IA, Abboudi H, Macphee, IA, Abboudi, H   +3 more
core   +1 more source

The Role of Systems Vaccinology in Understanding the Immune Defects to Vaccination in Solid Organ Transplant Recipients

Frontiers in Immunology, 2020
Solid organ transplant recipients (SOTRs) are at increased risk for many infections, whether viral, bacterial, or fungal, due to immunosuppressive therapy to prevent organ rejection.
Nicholas Scanlon, Nicholas Scanlon, Youssef Saklawi, Nadine Rouphael, Nadine Rouphael   +4 more
doaj   +1 more source