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Dose intensity for conditioning in allogeneic hematopoietic cell transplantation: can we recommend “when and for whom” in 2021?

open access: yesHaematologica, 2021
Allogeneic hematopoietic stem-cell transplantation is a potentially curative therapy for various hematologic diseases. An essential component of this procedure is the pre-transplant conditioning regimen, which should facilitate engraftment and reduce or
Nico Gagelmann, Nicolaus Kröger
doaj   +2 more sources

Reduced intensity conditioning allogeneic hematopoietic cell transplantation for adult acute myeloid leukemia in complete remission - a review from the Acute Leukemia Working Party of the EBMT

open access: yesHaematologica, 2015
Acute myeloid leukemia is the most common indication for an allogeneic hematopoietic cell transplant. The introduction of reduced intensity conditioning has expanded the recipient pool for transplantation, which has importantly made transplant an option ...
Salyka Sengsayadeth   +5 more
doaj   +2 more sources

Outcomes of Autologous Stem Cell Transplantation for Non-Hodgkin Lymphoma Patients at a Tertiary Referral Centre [PDF]

open access: yesMiddle East Journal of Cancer, 2023
Background: Autologous stem cell transplant (ASCT) has been used as a consolidative treatment modality in non-Hodgkin’s lymphoma (NHL), but its role in NHL management is still evolving.
Ajay Prakash, Hugh Goodman
doaj   +1 more source

Conditioning regimens for allogeneic hematopoietic cell transplantation in acute myeloid leukemia: Real-world data from the Japanese registry studies

open access: yesFrontiers in Oncology, 2022
Conditioning regimens play a crucial role in preventing relapse of acute myeloid leukemia (AML) following allogeneic hematopoietic cell transplantation (HCT).
Masamitsu Yanada   +4 more
doaj   +1 more source

Validation of the transplant conditioning intensity (TCI) index for allogeneic hematopoietic cell transplantation

open access: yesBone Marrow Transplantation, 2023
The intensity of the conditioning regimen given before allogeneic hematopoietic cell transplantation (allo-HCT) can vary substantially. To confirm the ability of the recently developed transplant conditioning intensity (TCI) score to stratify the ...
A. Spyridonidis   +29 more
semanticscholar   +1 more source

The consensus from The Chinese Society of Hematology on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell transplantation: 2021 update

open access: yesJournal of Hematology & Oncology, 2021
The consensus recommendations in 2018 from The Chinese Society of Hematology (CSH) on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell transplantation (allo-HSCT) facilitated the standardization of clinical ...
Xiao-hui Zhang   +19 more
semanticscholar   +1 more source

Thiotepa, Busulfan, Cyclophosphamide: Effective but Toxic Conditioning Regimen Prior to Autologous Hematopoietic Stem Cell Transplantation in Central Nervous System Lymphoma

open access: yesMedical Sciences, 2023
In primary central nervous system lymphoma, two-year progression-free survival rates of up to 63 percent have been reported for first-line autologous stem cell transplantation after conditioning with the thiotepa busulfan cyclophosphamide regimen ...
Lebon Delphine   +7 more
doaj   +1 more source

Personalized prediction of overall survival in patients with AML in non‐complete remission undergoing allo‐HCT

open access: yesCancer Medicine, 2021
Allogenic hematopoietic stem cell transplantation (allo‐HCT) is the standard treatment for acute myeloid leukemia (AML) in non‐complete remission (non‐CR); however, the prognosis is inconsistent.
Shigeki Hirabayashi   +18 more
doaj   +1 more source

A comparison between low intensity and reduced intensity conditioning in allogeneic hematopoietic stem cell transplantation for solid tumors

open access: yesHaematologica, 2008
Background Following different types of conditioning, allogeneic hematopoietic stem cell transplantation produces a graft-versus-tumor effect in patients with solid tumors.
Réka Conrad   +4 more
doaj   +1 more source

Classification of Conditioning Regimens for Bone Marrow Transplantation: Historical Background and Current Perspectives

open access: yesКлиническая онкогематология, 2017
Hematopoietic stem cells transplantation is a current standard treatment for many oncohematological diseases. The milestone of any type of transplantation is the choice of conditioning regimen.
Kapitolina Nikolaevna Melkova   +4 more
doaj   +1 more source

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