Results 121 to 130 of about 4,795,723 (322)

Transplant acceptance-inducing cells as an immune-conditioning therapy in renal transplantation

Transplant International, 2008
The transplant acceptance-inducing cell (TAIC) is a type of immunoregulatory macrophage with the capacity to specifically dampen allogeneic rejection responses to a degree allowing safe minimization of conventional immunosuppressive therapy. In the first part of this report, the production and phenotype of the human TAIC is described.
James A, Hutchinson, Paloma, Riquelme, Beate G, Brem-Exner, Maren, Schulze, Martina, Matthäi, Lutz, Renders, Ulrich, Kunzendorf, Edward K, Geissler, Fred, Fändrich   +8 more
openaire   +2 more sources

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics

Current Therapeutic Research
: Objectives: Treatment with tacrolimus requires strict control of the whole-blood concentration in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT).
Haruno Oku, BS, Saki Yoshida, BS, Takumi Hotta, BS, Hirohito Muroi, BS, Keizo Fukushima, PhD, Kei Irie, PhD, Tatsuya Hirano, BS, Yoshimitsu Shimomura, MD, Takayuki Ishikawa, MD, PhD, Hiroaki Ikesue, PhD, Nobuyuki Muroi, PhD, Tohru Hashida, PhD, Nobuyuki Sugioka, PhD   +12 more
doaj   +1 more source

HLA-DPB1 matching status has significant implications for recipients of unrelated donor stem cell transplants. [PDF]

, 2006
Studies in unrelated donor (UD) hematopoietic stem cell transplantations (HSCT) show an effect of the matching status of HLA-DPB1 on complications. We analyzed 423 UD-HSCT pairs. Most protocols included T-cell depletion (TCD).
Madrigal, JA, Marsh, SGE, Mayor, NP, Russell, NH, Shaw, BE   +4 more
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Non-myeloablative conditioning with allogeneic hematopoietic cell transplantation for the treatment of high-risk acute lymphoblastic leukemia

Haematologica, 2011
Background Allogeneic hematopoietic cell transplantation is a potentially curative treatment for patients with acute lymphoblastic leukemia. However, the majority of older adults with acute lymphoblastic leukemia are not candidates for myeloablative ...
Ron Ram, Rainer Storb, Brenda M. Sandmaier, David G. Maloney, Ann Woolfrey, Mary E. D. Flowers, Michael B. Maris, Ginna G. Laport, Thomas R. Chauncey, Thoralf Lange, Amelia A. Langston, Barry Storer, George E. Georges   +12 more
doaj   +1 more source

Steps in immunosuppression for renal transplantation [PDF]

, 1983
The authors provide a historical survey of the immunosuppressive agents that have been used to prevent allograft rejection.
Hakala, TR, Rosenthal, JT, Starzl, TE
core  

Engraftment kinetics and graft failure after single umbilical cord blood transplantation using a myeloablative conditioning regimen

Haematologica, 2014
Umbilical cord blood transplant recipients are exposed to an increased risk of graft failure, a complication leading to a higher rate of transplant-related mortality. The decision and timing to offer a second transplant after graft failure is challenging.
A. Ruggeri, M. Labopin, M. Sormani, G. Sanz, J. Sanz, F. Volt, G. Michel, F. Locatelli, C. D. de Heredia, T. O'Brien, W. Arcese, A. Iori, S. Querol, G. Kogler, L. Lecchi, F. Pouthier, F. Garnier, C. Navarrete, E. Baudoux, J. Fernandes, C. Kenzey, M. Eapen, E. Gluckman, V. Rocha, R. Saccardi   +24 more
semanticscholar   +1 more source

MECHANICAL CONDITIONING OF GREENHOUSE-GROWN TRANSPLANTS [PDF]

HortScience, 1992
Since chemical growth retardants are no longer labelled for use on vegetable transplants, mechanical conditioning provides an alternative method of controlling excessive stem elongation under greenhouse conditions. Mechanical conditioning includes brushing or shaking treatments that physically impact or displace the plant and generally reduce plant ...
openaire   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source