Results 91 to 100 of about 1,026 (124)

Streptozotocin-induced renal hemodynamic changes in isogenic Lewis rats: a kidney transplant study

American Journal of Physiology-Renal Physiology, 1993
Streptozotocin (STZ)-induced diabetes mellitus is associated with decreased renal clearances of inulin and p-aminohippurate (PAH). The present experiments were designed to determine whether STZ-induced renal hemodynamic changes are due to the drug per se, rather than to the diabetic state that it induces.
P, Churchill, M, Churchill, A, Bidani, J, Dunbar   +3 more
openaire   +2 more sources

Differences in the osteoinductive potential of transplanted isogeneic dental structures of the rat

Cells Tissues Organs, 1977
Pulp tissue, enamel and incisal and basal dentine of the mandibular incisor were taken from one litter of rats and transplanted subcutaneously or intracerebrally to sex-matched, 5-day-old animals of the subsequent litter of the same parents. As sham-operations the mere transplantation instrument was inserted into the transplantation sites.
V, Luostarinen, O, Rönning
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Reversal of the Effect of Pinealectomy in Female Rats by Multiple Isogeneic Pineal Transplants

Endocrinology, 1965
Pinealectomy resulted in a significantly increased incidence of vaginal smears that demonstrated estrous phases in female rats under varying degrees of ambient illumination, including constant light. Pineal glands transplanted intramuscularly or under the renal capsule as isografts within a strictly inbred strain show excellent histological survival ...
R F, Gittes, E W, Chu
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Isogenic fish sperm produced by transplanting gynogenetic haploid-derived germ cells

Biology of Reproduction
Abstract Artificially induced haploidy is lethal in vertebrates, although it is useful for genetic screening and genome editing due to its single set of genomes. Haploid embryonic stem (ES) cell lines in mammals contribute to genetic studies and the production of gametes derived from haploid ES cells.
Tsuyoshi, Nagasaka, Takafumi, Fujimoto, Taiju, Saito, Etsuro, Yamaha, Katsutoshi, Arai   +4 more
openaire   +2 more sources

A Model of Reversible Uremia Employing Isogenic Kidney Transplantation in the Rat

Scandinavian Journal of Urology and Nephrology, 1993
Kidney transplanted patients with normalized kidney function may still exhibit a variety of problems such as bone problems, vascularly problems, and hormonal dysfunctions. A part of the symptoms may be persisting uremic symptoms, secondary to the pretransplanted period of chronic uremia.
E, Lewin, H, Colstrup, V, Pless, J, Ladefoged, K, Olgaard   +4 more
openaire   +2 more sources

Morphogenetic potential of rat growth cartilages as isogeneic transplants in the interparietal suture area

Archives of Oral Biology, 1982
The proximal end of the tibia or the spheno-occipital synchondrosis with some adjoining bone were isogeneically transplanted across the interparietal suture of 10-day-old rats. As a sham procedure, a piece of calvarium traversed by a part of the interparietal suture was interchanged between pairs of animals. Untreated rats served as controls.
O, Rönning, S, Kylämarkula
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Pregression of perineurial cell basement membrane in a human diabetic following isogenic pancreas transplant

Acta Neuropathologica, 1989
Perineurial cell basement membrane (PCBM) thickening is a consistent feature in diabetes mellitus (DM) and may have relevance to the cause of DM neuropathy. In this ultrastructural morphometric study of identical twins discordant for DM, we found that the PCBM was significantly thicker in the dermal nerves of the diabetic twin.
J L, Beggs, P C, Johnson, A G, Olafsen, C J, Watkins, J H, Targovnik, L J, Koep   +5 more
openaire   +2 more sources

Reversal of diabetes by isogeneic transplantation of cultured pancreatic islets.

Endokrinologie, 1981
Pancreatic islets were isolated by collagenase digestion from female Wistar rats and cultured at 20 mmol/l glucose. The enhancement of Mg++ concentration from 0.8 mmol/l up to 5.3 mmol/l had a protecting effect on the glucose-induced insulin release in the subsequent short-time incubation and prevented the age-depending decrease of B-cell function ...
B, Ziegler, D, Lorenz, H, Lippert, R, Butter, M, Ziegler, H J, Hahn   +5 more
openaire   +1 more source

Restoration of muscle fibers and satellite cells after isogenic MSC transplantation with microdystrophin gene delivery

Biochemical and Biophysical Research Communications, 2012
Duchenne muscular dystrophy is the most prevalent inheritable muscle disease. Transplantation of autologous stem cells with gene direction is an ideal therapeutic approach for the disease. The current study aimed to investigate the restoration of myofibers in mdx mice after mdx bone marrow-derived mesenchymal stem cell (mMSC) transplantation with human
Shan-wei, Feng, Fei, Chen, Jiqing, Cao, Mei-juan, Yu, Ying-yin, Liang, Xin-ming, Song, Cheng, Zhang   +6 more
openaire   +2 more sources

Evaluation of the Hormonal Function and Histological Features of Heterotopic Isogenic Ovarian Transplantation in Rats

Plastic and Reconstructive Surgery, 2003
The purpose of the study was to determine the feasibility of preserving ovarian function after heterotopic transplantation by means of microvascular anastomosis of the transplanted vascular pedicles to a set of preselected vessels. Six groups of 10 Sprague-Dawley inbred rats were used in this study. Group I underwent bilateral ovariectomy operation and
David T W, Chiu, Guoli, Hu
openaire   +2 more sources