Results 1 to 10 of about 1,124,538 (196)

Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Delayed Wound Healing in Diabetic Rats [PDF]

Journal of Diabetes Research, 2013
In this paper, we established a delayed wound healing model on diabetic rat to mimic the pathophysiology of clinical patients who suffered from diabetic foot ulcers.
Jiangbo Wan, Liulu Xia, Wenjia Liang, Yi Liu, Qian Cai   +4 more
doaj   +4 more sources

Noninvasive quantification of granzyme B in cardiac allograft rejection using targeted ultrasound imaging [PDF]

Frontiers in Immunology, 2023
ObjectiveEndomyocardial biopsy is the gold standard method for the diagnosis of cardiac allograft rejection. However, it causes damage to the heart.
Yunjie Jin, Yunjie Jin, Peng Gao, Lifei Liang, Lifei Liang, Yuhang Wang, Jiawei Li, Jiawei Li, Jiyan Wang, Jiyan Wang, Jiangang Hou, Cheng Yang, Cheng Yang, Cheng Yang, Xiaolin Wang   +14 more
doaj   +4 more sources

Role of Hyperglycemia in Isogeneic Islet Transplantation: An Experimental Animal Study [PDF]

Experimental and Clinical Endocrinology & Diabetes, 2008
Study the role of hyperglycemia-induced beta cell loss on grafted islet destruction.Male inbred rats were made diabetic by streptozotocin administration and used as islet donors and/or isograft recipients to probe directly the role of hyperglycemia as an important determinant of transplanted islet fate, following exclusion of immune-related causes of ...
I, Nomikos, K, Kalogerakos, E, Athanasiou, E, Plakokefalos, E, Plakokefales, D, Sioutopoulou, M, Satra, N C, Vamvakopoulos   +7 more
semanticscholar   +5 more sources

High-dose atorvastatin reduces oxidative stress of ischemia/reperfusion injury after isogeneic kidney transplantation in rats: in vivo, preclinical, case–control, open-label study [PDF]

Renal Replacement Therapy, 2023
Background Renal ischemia/reperfusion injury is an unavoidable event in transplantation in which free radical-mediated injury determines release of pro-inflammatory cytokines and activation of innate immunity.
Giacomo Cusumano, Edoardo Cola, Gionata Spagnoletti, Anna Severino, Simona Giubilato, Egidio Stigliano, Maria Emiliana Caristo, Gisella Vischini, Giovanna Liuzzo, Maria Paola Salerno, Filippo Crea, Jacopo Romagnoli   +11 more
doaj   +3 more sources

Investigation of the expressions of MMPs and TIMPs between isogeneic and allogeneic rat aortic transplantation

Molecular Medicine Reports, 2018
The present study investigated the effects of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in transplantation-associated arteriosclerosis by observing their expression in transplanted aortas in rats. Allogenic and isogenic abdominal aortic transplantations were performed and grafts were removed from the recipients
Si-Dong, Wei, Ding, Cao, Xue-Song, Xu, He, Bai, Hao, Wu, Meng-Hao, Wang   +5 more
semanticscholar   +5 more sources

ISOGENEIC ISLET TRANSPLANTATION

Transplantation, 1991
81557
LOFTUS, IM, LONDON, NJM, THIRDBOROUGH, SM, BELL, PRF, JAMES, RFL   +4 more
openaire   +4 more sources

The role of HIF-1α-VEGF pathway in bronchiolitis obliterans after lung transplantation

Journal of Cardiothoracic Surgery, 2019
Background Graft function may be affected if the organ is exposed to hypoxia. We hypothesized that bronchiolitis obliterans (BO) after lung transplantation is associated with hypoxia-inducible factor-1α (HIF-1α). This study compares the expression of HIF-
Haichao Xu, Abudumailamu Abuduwufuer, Wang Lv, Zhenyu Zhou, Yunhai Yang, Chong Zhang, Jian Hu   +6 more
doaj   +2 more sources

Transplanting old organs promotes senescence in young recipients. [PDF]

Am J Transplant, 2023
In clinical organ transplantation, donor and recipient age may differ substantially. Old donor organs accumulate senescent cells that have the capacity to induce senescence in naïve cells.
Iske J, Roesel MJ, Martin F, Schroeter A, Matsunaga T, Maenosono R, Tripathi U, Xiao Y, Nian Y, Caldarone BJ, Vondran FWR, Sage PT, Azuma H, Abdi R, Elkhal A, Pirtskhalava T, Tchkonia T, Kirkland JL, Zhou H, Tullius SG.   +19 more
europepmc   +2 more sources

Two Compartment Evaluation of Liver Grafts During Acellular Room Temperature Machine Perfusion (acRTMP) in a Rat Liver Transplant Model [PDF]

Frontiers in Medicine, 2022
BackgroundSubnormothermic machine perfusion (SNMP) of liver grafts is currently less clinically developed than normothermic and hypothermic approaches, but may have logistical advantages.
Nader Abraham, Min Zhang, Paul Cray, Qimeng Gao, Kannan P. Samy, Ryan Neill, Greta Cywinska, JonCarlo Migaly, Riley Kahan, Arya Pontula, Samantha E. Halpern, Caroline Rush, Jude Penaflor, Samuel J. Kesseli, Madison Krischak, Mingqing Song, Matthew G. Hartwig, Justin J. Pollara, Andrew S. Barbas   +18 more
doaj   +2 more sources

Immunosuppressive protocols with tacrolimus after cryopreserved aortal allotransplantation in rats. [PDF]

PLoS ONE, 2018
OBJECTIVES AND DESIGN:The aim of our study was to simulate in rats all aspects and techniques used in our new clinical program of cryopreserved alloarterial transplantation and investigate the influence of two immunosuppressive protocols with tacrolimus ...
Rudolf Spunda, Jan Hruby, Pavel Mericka, Mikulas Mlcek, Ondrej Pecha, Kathrin Splith, Moritz Schmelzle, Felix Krenzien, Jaroslav Lindner, Ivan Matia, Miroslav Spacek   +10 more
doaj   +2 more sources