Results 21 to 30 of about 1,124,538 (196)

Hydrogen-Enriched Preservation Protects the Isogeneic Intestinal Graft and Amends Recipient Gastric Function During Transplantation

Transplantation, 2011
B. Buchholz, K. Masutani, T. Kawamura, Ximei Peng, Y. Toyoda, T. Billiar, A. Bauer, A. Nakao   +7 more
semanticscholar   +2 more sources

Whole‐Genome Sequencing Revealed a Late‐Maturing Isogenic Rice Koshihikari Integrated with Hd16 Gene Derived from an Ise Shrine Mutant

International Journal of Genomics, Volume 2022, Issue 1, 2022., 2022
We identified the key genes controlling the late maturation of the Japonica cultivar Isehikari, which was found at Ise Jingu Shrine and matures 6 days later than Koshihikari. We conducted a genetics‐based approach through this study. First, the latest mature plants, which flowered later than Isehikari, were segregated in the F2 and F3 generations of ...
Motonori Tomita, Ryotaro Tokuyama, Shosuke Matsumoto, Kazuo Ishii, Vijay Gahlaut   +4 more
wiley   +1 more source

A Comprehensive Update of Cerebral Organoids between Applications and Challenges

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
The basic technology of stem cells has been developed and created organoids, which have established a strong interest in regenerative medicine. Different cell types have been used to generate cerebral organoids, which include interneurons and oligodendrocytes (OLs). OLs are fundamental for brain development.
Xiaodong Li, Abdullah Shopit, Jingmin Wang, Sandra Moreno   +3 more
wiley   +1 more source

Cuff Anastomosis of Both Renal Artery and Vein to Minimize Thrombosis: A Novel Method of Kidney Transplantation in Mice

Journal of Investigative Surgery, 2022
Objectives Anastomosis of renal artery and renal vein in mouse models of kidney transplantation is technically challenging. Conventional technique using suture may result in vascular thrombosis.
Yi Yu, Jun Li, Zirong Bi, Chenglin Wu, Shicong Yang, Qifeng Jiang, Ronghai Deng, Qian Fu, Longshan Liu, Changxi Wang   +9 more
doaj   +1 more source

Adaptive Immunity and Pathogenesis of Diabetes: Insights Provided by the α4–Integrin Deficient NOD Mouse

Cells, 2020
Background: The spontaneously diabetic “non-obese diabetic” (NOD) mouse is a faithful model of human type-1 diabetes (T1D). Methods: Given the pivotal role of α4 integrin (CD49d) in other autoimmune diseases, we generated NOD mice with α4-deficient ...
Salim Oulghazi, Sarah K. Wegner, Gabriele Spohn, Nina Müller, Sabine Harenkamp, Albrecht Stenzinger, Thalia Papayannopoulou, Halvard Bonig   +7 more
doaj   +1 more source

Intrauterine Transplantation of Isogenic Pancreatic Islets in Experimental Diabetic Rats.

Journal of Veterinary Medical Science, 1994
The effect of intrauterine transplantation (IU group) as a potential immunologically privileged site on the diabetic state of the recipient was compared with that of conventional intraperitoneal transplantation (IP group) using Fisher 344 rats. Islets were isolated from the pancreata of normal rats and transplanted into the uterus and peritoneal cavity
SAKONJU, Iwao, TAURA, Yasuho, NAKAICHI, Munekazu, NAKAMA, Sanenori, KAGABU, Satoshi   +4 more
openaire   +3 more sources

Acute Ischemia/Reperfusion Injury After Isogeneic Kidney Transplantation Is Mitigated in a Rat Model of Chronic Renal Failure

American Journal of Transplantation, 2003
The influence of chronic renal failure on renal susceptibility to an acute ischemic insult was evaluated. Recipient Lewis rats were randomly assigned to undergo 5/6 nephrectomy (chronic renal failure, CRF) or sham operation (normal renal function, NRF ...
S. Vercauteren, D. Ysebaert, A. R. Van Rompay, K. D. De Greef, M. de Broe   +4 more
semanticscholar   +1 more source

Transplante isogênico de ilhotas de Langerhans no fígado de ratos: metodologia para separação e purificação das ilhotas de Langerhans Isogenic islet transplantation on the rat liver: Method for isolation and purification of the rat islets

Arquivos de Gastroenterologia, 2000
A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina mantendo os níveis glicêmicos dentro da normalidade.
Eleazar CHAIB, Apostolos PAPALOIS, Ingrid G. M. BRONS, Roy Y. CALNE   +3 more
doaj   +1 more source

Bortezomib attenuates renal interstitial fibrosis in kidney transplantation via regulating the EMT induced by TNF‐α‐Smurf1‐Akt‐mTOR‐P70S6K pathway

Journal of Cellular and Molecular Medicine, Volume 23, Issue 8, Page 5390-5402, August 2019., 2019
Abstract Allograft interstitial fibrosis was characterized by massive extracellular matrix deposition caused by activated fibroblasts and myofibroblasts. Epithelial‐mesenchymal transition (EMT) is recognized as an important source of myofibroblasts contributing to the pathogenesis of allograft interstitial fibrosis.
Jiajun Zhou, Hong Cheng, Zijie Wang, Hao Chen, Chuanjian Suo, Hengcheng Zhang, Jiayi Zhang, Yanhao Yang, Liang Geng, Ming Gu, Ruoyun Tan   +10 more
wiley   +1 more source

Renal Allograft Rejection: Noninvasive Ultrasound‐ and MRI‐Based Diagnostics

Contrast Media &Molecular Imaging, Volume 2019, Issue 1, 2019., 2019
To date, allogeneic kidney transplantation remains the best available therapeutic option for patients with end‐stage renal disease regarding overall survival and quality of life. Despite the advancements in immunosuppressive drugs and protocols, episodes of acute allograft rejection, a sterile inflammatory process, continue to endanger allograft ...
Ulrich Jehn, Katharina Schuette-Nuetgen, Dominik Kentrup, Verena Hoerr, Stefan Reuter, Sarah Ohrndorf   +5 more
wiley   +1 more source