Results 141 to 150 of about 5,891 (253)

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

TRANSPLANTE AUTÓLOGO DE CÉLULAS TRONCO HEMATOPOIETICAS EM LINFOMA DE HODGKIN QUIMIORESISTENTE APÓS USO DE BRENTUXIMAB E/OU INIBIDORES DE PD1: EXPERIÊNCIA DE UM CENTRO BRASILEIRO

Hematology, Transfusion and Cell Therapy, 2020
D.A.G. Eguez, A.L. Stollenwerk, A.P. Graça, P.H.A. Moraes, K.Z. Cecyn, M.J.F.S. Junior, R.F.M. Nunes, K.P. Melillo, R.M.A. Passos, L.L.M. Perobelli   +9 more
doaj   +1 more source

Liquid Metal Resistive Sensing Architectures for Measuring Diaphragm Strain Responses on Obstructed Surfaces

Advanced Materials Technologies, EarlyView.
A liquid metal‐based strain‐sensing architecture to measure the deformation of a circular diaphragm against obstructed surfaces is formulated using finite element modeling and confocal imaging to establish the mechanical framework and is utilized to control diaphragm‐induced confinement on a bead array, as validated by biomolecular loading level ...
Abdullah‐Bin Siddique, Jui‐Hong Weng, Deng‐Kai Yang, Chia‐Fu Chou, Nathan S. Swami   +4 more
wiley   +1 more source

Barriers to kidney transplant referral in the state of Minas Gerais: nephrologists' perspectives. [PDF]

J Bras Nefrol
Nogueira CM, Martins LC, Sanders-Pinheiro H.   +2 more
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

ABTO Brazilian Transplant Registry and ISHLT Heart Transplant Registry: An Important/Valuable Partnership. [PDF]

Arq Bras Cardiol
Atik FA, Pego-Fernandes PM, Mejia JA, Goldraich LA, Marcondes-Braga FG, Azeka E, Figueira FA, Garcia VD, Haddad L, Cherikh W, Stehlik J, Cogswell R.   +11 more
europepmc   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Rapamicina não induz apoptose em cultura de linfócitos [PDF]

, 2005
Carpio, Virna Nowotny, Dias, E.C.A., Manfro, Roberto Ceratti, Prochnow, T.A., Gonçalves, Luiz Felipe Santos   +4 more
core   +1 more source

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

Diabete melito pós-transplante (DMPT) não influencia a sobrevida de enxertos e pacientes transplantados renais em 10 anos de seguimento [PDF]

, 2005
Zelmanovitz, Themis, Copstein, L.A., Garcia, J.P., Manfro, Roberto Ceratti, Gonçalves, Luiz Felipe Santos   +4 more
core   +1 more source