Results 101 to 110 of about 5,385,238 (242)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The role of industrial design in addressing the disparity between user perceptions of public and private transport

, 2007
This paper examines the disparity between the perceptions of private and public transport from those who might exercise choice between them. There is a great body of literature concerning the identification of problems in public transport mobility.
Coxon, Selby, Napper, Robbie, Allen, Jonathon (R13609)   +2 more
core  

New Zealand transport domain plan [PDF]

, 2016
The Transport Domain Plan (the Domain Plan) ensures that the transport sector has the right data and information. It aims to help the transport sector to better coordinate how agencies collect and manage data and knowledge, and ensure that existing ...
Ministry of Transport (New Zealand)
core  

Effects of Short- and Long-Distance Road Transport and Temperament on the Magnitude of β-Endorphin Response in Limousine Bulls

Ruminants
The purpose of this study was to evaluate the effects of short- and long-distance road transport and temperament on β-endorphin (β-EP) concentrations in 23 Limousine bulls, aged 12 ± 2 months old, taking into account the related effect on body weight (BW)
Esterina Fazio, Salvatore Cavaleri, Pietro Medica, Cristina Cravana, Deborah La Fauci   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Metropolitan passenger transport routes [cartographic material] /

, 1939
Includes inserts of Perth city block and Spearwood-Jandapot-Forrestdale-Armadale area.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map-vn4781383.
Western Australia. Transport Board
core  

Effects of dietary guanidinoacetic acid supplementation on serum reproductive hormone levels and ovarian function in transport-stressed growing-laying hens

Siliao yanjiu
This study aimed to investigate the effects of dietary guanidinoacetic acid supplementation on the serum hormone levels and ovarian function in transport-stressed growing-laying hens.
GUO Zhiyou, REN Jinli, SONG Zhibo, XIE Hongmei   +3 more
doaj  

Serum Oxidative Status and Thiol-Disulfide Homeostasis in Late-Gestation Holstein Heifers with and Without a History of Mid-Gestation Transport

Veterinary Sciences
Pregnancy in dairy cattle is characterized by marked metabolic adaptations that may influence oxidative balance. In this study, oxidative stress markers and thiol–disulfide homeostasis were evaluated in transported and non-transported Holstein heifers ...
Güzin Özkurt, Recep Bozkurt, Tamer Kayar, Seynur Ali Hatib, Ayşenur Baydar   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source