Results 31 to 40 of about 5,934 (256)

Is Scientific Knowledge Useful for Policy Analysis? A Peculiar Theorem Says: No

Journal of Causal Inference, 2014
Conventional wisdom dictates that the more we know about a problem domain the easier it is to predict the effects of policies in that domain. Strangely, this wisdom is not sanctioned by formal analysis, when the notions of “knowledge” and “policy” are ...
Pearl Judea
doaj   +1 more source

S.A.F.E. An emergency project experimentation

Agathón, 2018
The proposed paper describes a project research activity on the theme of temporary housing modules needed to cope with emergency situations. The product is designed to be placed in the segment between the provision of first aid shelters (currently solved
Francesca Castagneto
doaj   +1 more source

Transport and transporters in the endoplasmic reticulum

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2007
Enzyme activities localized in the luminal compartment of the endoplasmic reticulum are integrated into the cellular metabolism by transmembrane fluxes of their substrates, products and/or cofactors. Most compounds involved are bulky, polar or even charged; hence, they cannot be expected to diffuse through lipid bilayers.
CSALA, M., MARCOLONGO, P., LIZAK, B., SENESI, S., MARGITTAI, E., FULCERI, R., MAGYAR, J. E., BENEDETTI, A., BANHEGYI, G.   +8 more
openaire   +5 more sources

Transportability of Conclusions From Confined Field Trials: A Case Study Using the Virus Resistant Transgenic Bean Developed in Brazil

Frontiers in Bioengineering and Biotechnology, 2020
The conceptual framework for Data Transportability, builds on the premise that well-designed studies conducted for the environmental and food/feed risk assessment of transgenic crops may be transportable across geographies.
Facundo Vesprini, Facundo Vesprini, Andrés Ignacio Maggi, Andrés Ignacio Maggi, Magdalena López Olaciregui, Magdalena López Olaciregui, Natalia Andrea Módena, Natalia Andrea Módena   +7 more
doaj   +1 more source

International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality

npj Digital Medicine, 2022
Given the growing number of prediction algorithms developed to predict COVID-19 mortality, we evaluated the transportability of a mortality prediction algorithm using a multi-national network of healthcare systems.
Griffin M. Weber, Chuan Hong, Zongqi Xia, Nathan P. Palmer, Paul Avillach, Sehi L’Yi, Mark S. Keller, Shawn N. Murphy, Alba Gutiérrez-Sacristán, Clara-Lea Bonzel, Arnaud Serret-Larmande, Antoine Neuraz, Gilbert S. Omenn, Shyam Visweswaran, Jeffrey G. Klann, Andrew M. South, Ne Hooi Will Loh, Mario Cannataro, Brett K. Beaulieu-Jones, Riccardo Bellazzi, Giuseppe Agapito, Mario Alessiani, Bruce J. Aronow, Douglas S. Bell, Vincent Benoit, Florence T. Bourgeois, Luca Chiovato, Kelly Cho, Arianna Dagliati, Scott L. DuVall, Noelia García Barrio, David A. Hanauer, Yuk-Lam Ho, John H. Holmes, Richard W. Issitt, Molei Liu, Yuan Luo, Kristine E. Lynch, Sarah E. Maidlow, Alberto Malovini, Kenneth D. Mandl, Chengsheng Mao, Michael E. Matheny, Jason H. Moore, Jeffrey S. Morris, Michele Morris, Danielle L. Mowery, Kee Yuan Ngiam, Lav P. Patel, Miguel Pedrera-Jimenez, Rachel B. Ramoni, Emily R. Schriver, Petra Schubert, Pablo Serrano Balazote, Anastasia Spiridou, Amelia L. M. Tan, Byorn W. L. Tan, Valentina Tibollo, Carlo Torti, Enrico M. Trecarichi, Xuan Wang, The Consortium for Clinical Characterization of COVID-19 by EHR (4CE), Isaac S. Kohane, Tianxi Cai, Gabriel A. Brat   +64 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Feasibility of sliding base isolation for rubble stone masonry buildings in the Himalayan Mountain range

Frontiers in Built Environment
This paper studied the feasibility of a sliding base isolation layer to be used in rubble stone masonry buildings in rural areas in the Himalayan Mountain range to provide robust protection to important building like schools against strong earthquakes ...
Yusuke Suzuki, Mayako Tada, Ryuta Enokida, Jiro Takagi, Yoshikazu Araki, Sanjay Pareek, Sanghun Lee, Kohju Ikago, Jia Guo, Kshitij C. Shrestha, Iori Fukuda, Takeshi Masui   +11 more
doaj   +1 more source

Transportation and the Environment [PDF]

Annual Review of Environment and Resources, 2011
The growth of CO2-intensive transport, mobility and the impact of transport on the environment are reviewed. The recent global exponential growth in transport is unsustainable and must end unless the transport sector can decarbonize. The paper examines solutions for low-carbon transport systems; the behavioral options; possible demand reduction; the ...
Banister, D., Anderton, K., Bonilla, D., Givoni, M., Schwanen, T.   +4 more
openaire   +3 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source