Results 91 to 100 of about 2,898,574 (357)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

A Terrorism Analysis of the April 14, 2014, Bus Terminal Bombing in Abuja, Nigeria [PDF]

open access: yes, 2014
This Transportation Security Perspective is the fourth in a continuing series produced by the National Transportation Safety and Security Center of the Mineta Transportation Institute.
Butterworth, Bruce R., Jenkins, Brian M.
core   +1 more source

Accessibility of islands: towards a new geography based on transportation modes and choices [PDF]

open access: yesIsland Studies Journal, 2014
Accessibility is a multifaceted concept that expresses the case of access between two points in space. For islands, accessibility is a key quality, since isolation and small size considered as inherent characteristics of “islandness”.
Sofia Karampela   +2 more
doaj  

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Retracted: A Novel Traffic Surveillance System Using an Uncalibrated Camera

open access: yesJournal of Advanced Transportation, 2023
Journal of Advanced Transportation
doaj   +1 more source

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