Results 61 to 70 of about 2,898,574 (357)
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Active Transportation for America [PDF]
, 2008 In this era of traffic congestion, high gas prices, climate change, an obesity epidemic, and fiscal constraints, federal transportation funding has reached a critical crossroads.Decades of car-centered transportation policies have dead-ended in chronic ...
core
Expenditures on Public Transportation [PDF]
, 1999 Public transportation expenditures consumed 6 percent of the average household\u27s transporation budget in 1997, divided between intracity and intercity travel (22 percent and 78 percent of total public transportation expenditures, respectively ...
Bureau of Labor Statistics
core +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
The Future of California Transportation Revenue [PDF]
, 2018 Stable, predictable, and adequate transportation revenues are needed if California is to plan and deliver an excellent transportation system. This report provides a brief history of transportation revenue policies and potential futures in California.
Agrawal, Asha Weinstein +2 more
core +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Rail Passenger Selective Screening Summit, MTI S-09-01 [PDF]
, 2009 This publication is an edited transcript of the Rail Passenger Selective Screening Summit, which was co-sponsored by MTI and the American Public Transportation Association (APTA) in Chicago, Illinois on June 18, 2009, during APTA´s annual Rail Conference.
MTI
core +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
Analisis Industri Bisnis Jasa Online Ride Sharing di Indonesia
Esensi: Jurnal Bisnis dan Manajemen, 2018 Analysis of Online Ride Sharing Business Industry in IndonesiaInnovation in transportation sector with sharing economy principal has create new service sector which is named online ride sharing service.
Berto Mulia Wibawa +2 more
doaj +1 more source