Results 41 to 50 of about 1,191,599 (308)

The many “costs” of transportation: Examining what cancer caregivers experience as transportation obstacles

Cancer Medicine, 2023
Background Transportation has been identified as a specific source of burden for cancer caregivers. This study examined cancer caregivers' subjective experiences and objectives costs associated with transportation over a 6‐month period of providing end ...
Maria D. Thomson, Courtney Harold Van Houtven, Rebecca Xu, Laura A. Siminoff   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Application of a discrete approach to designing the transport component of municipal solid waste logistics

Вестник СибАДИ
Introduction. The growth of the urban area has led to the need to transfer landfills for the disposal of solid municipal (household) waste (MSW) to more remote locations on new sites. Representations and approaches to cargo transportation planning are an
E. E. Vitvitsky, E. S. Galaktionova, N. I. Yuryeva   +2 more
doaj   +1 more source

Sensitivity Analysis of Transportation Production Costs in Indonesia [PDF]

, 2008
The transportation production cost (TPC) considerably has strong influence to the national economic condition. This paper focused on the analysis of the transportation production cost sensitivity in relation to the variation of the external affecting ...
Armijaya, H. (Henry), Munandar, A. S. (Ari), Rahardjo, A. (Agung), Sjafruddin, A. (Ade)   +3 more
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

THE IMPACT OF TRANSPORTATION COSTS ON ECONOMIC PERFORMANCES IN CROP PRODUCTION

Ekonomika Poljoprivrede (1979), 2020
Transport activity has significant implications for the other sectors activities, including agriculture and agribusiness. Transportation costs represent a significant determinant of total operating costs, and therefore the selling price, which affects ...
Bojan Savić, Mladen Petrović, Zorica Vasiljević   +2 more
doaj   +1 more source

Getting Around When You’re Just Getting By: The Travel Behavior and Transportation Expenditures of Low-Income Adults, MTI Report 10-02 [PDF]

, 2011
How much do people with limited resources pay for cars, public transit, and other means of travel? How does their transportation behavior change during periods of falling employment and rising fuel prices?
Abel, Sarah, Agrawal, Asha Weinstein, Blumenberg, Evelyn A., Pierce, Gregory   +3 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source