Results 41 to 50 of about 179,749 (303)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Logistics in the Road Modal: A costs approach in function of the distance of transport and type of vehicle

open access: yesSemina: Ciências Exatas e Tecnológicas, 2009
With the increase in soybean production in the last couple of years - transported mostly by road - Brazil has faced great transportation problems , mainly due to lack of infrastructure and poor road conditions.
Thiago Epiphanio Pereira   +1 more
doaj  

Infrastructure, Geographical Disadvantage, and Transport Costs [PDF]

open access: yes, 1999
December 1999 The median landlocked country has only 30 percent of the trade volume of the median coastal economy. Halving transport costs increases that trade volume by a factor of five. Improving the standard of infrastructure from that of the bottom quarter of countries to that of the median country increases trade by 50 percent.
Limao, Nuno, Venables, Anthony J.
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Generalized Transport Costs in Intermodal Freight Transport

open access: yesProcedia - Social and Behavioral Sciences, 2012
AbstractIntermodal transport solutions, implying non-road freight transport on the long-haul, can contribute to the advance of more energy efficient transportation systems. This paper presents a model for analyzing the generalized transport cost of an intermodal transport solution.
Hanssen, Thor-Erik Sandberg   +2 more
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

THE IMPACT OF TRANSPORTATION COSTS ON ECONOMIC PERFORMANCES IN CROP PRODUCTION

open access: yesEkonomika Poljoprivrede (1979), 2020
Transport activity has significant implications for the other sectors activities, including agriculture and agribusiness. Transportation costs represent a significant determinant of total operating costs, and therefore the selling price, which affects ...
Bojan Savić   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Hybrid SuperHyperSoft Model for Evaluation of Comprehensive Transportation Efficiency: Analysis and Results [PDF]

open access: yesNeutrosophic Sets and Systems
In this research, we investigate the features of comprehensive transportation efficiency assessment. Optimizing the energy-saving and efficient comprehensive transportation structure is essential to further lowering logistics costs.
Zigeng Wen, Jie Liu, Jianchang Huang
doaj   +1 more source

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