Results 71 to 80 of about 179,749 (303)

Freight Rates and the Commercial-Nautical Revolution from the Perspective of a Minor Mediterranean Port-City

open access: yesAnales de la Universidad de Alicante. Historia Medieval
Roberto Lopez’s influential thesis of post-1350 economic retrenchment has long served as both a cornerstone and a point of contention in the historiography of late medieval Europe.
Nicolò Villanti
doaj   +1 more source

ANALYSIS OF THEORETICAL APPROACHES TO ESTIMATION OF ECONOMIC VALUATION OF TRAVEL TIME VARIABILITY AND THE VALUE OF TRAVEL TIME SAVINGS OF URBAN PASSENGER TRANSPORT

open access: yesВестник университета, 2018
The overview of some theoretical approaches to the mechanism of economic valuation of travel time variability and the value of travel time savings of urban passenger transport is provided.
V. Donchenko, R. Filippova
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Development of a Methodology for Assessment of Crash Costs at Highway-Rail Grade Crossings in Nebraska [PDF]

open access: yes
An accurate measure of crash costs is required to support effective decision-making about transportation investments. In particular, underinvestment will occur if measurement fails to capture the full cost of crashes.
Mid-America Transportation Center   +2 more
core  

Transportation Economic Trends 2017 [PDF]

open access: yes
The report has eight chapters: - Chapter 1 introduces the Transportation Services Index, a monthly summary of freight and passenger movement. - Chapter 2 explains what transportation contributes to the American economy.
Brumbaugh, Stephen   +3 more
core   +1 more source

Integral criteria for transportation cost inequalities

open access: yesElectronic Communications in Probability, 2006
In this paper, we provide a characterization of a large class of transportation-cost inequalities in terms of exponential integrability of the cost function under the reference probability measure. Our results completely extend the previous works by Djellout, Guilin and Wu and Bolley and Villani.
openaire   +5 more sources

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