Results 41 to 50 of about 1,006,093 (289)

Attracting and Retaining Women in the Transportation Industry [PDF]

open access: yes, 2019
This study synthesized previously conducted research and identified additional research needed to attract, promote, and retain women in the transportation industry.
Bertini, Robert L., Godfrey, Jodi
core   +1 more source

From individual behaviour to an evaluation of the collective evolution of crowds along footbridges

open access: yes, 2016
This paper proposes a crowd dynamic macroscopic model grounded on microscopic phenomenological observations which are upscaled by means of a formal mathematical procedure.
Bruno, Luca   +2 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

IMPLEMENTATION OF POLICIES CONCERNING MANAGEMENT AND ENGINEERING OF TRAFFIC AND ROAD TRANSPORTATION AND PARKING IN UBUD SUB-DISTRICT

open access: yesE-Journal of Cultural Studies, 2023
Management and engineering of traffic and road transportation are programs initiated by the Gianyar Regency government with the aim of achieving an integrated transportation system that ensures safety, security, order, smoothness, regularity, success ...
I Made Artayasa
doaj   +1 more source

Work Organisation and Innovation - Case Study: Bombardier, Belgium [PDF]

open access: yes, 2013
[Excerpt] Bombardier Inc. is headquartered in Montréal, Canada and is structured around two businesses of almost the same size: aerospace and transportation. It has 76 production and engineering sites in more than 60 countries, and employs 65,400 people.
De Hauw, Yolien, Maenen, Seth
core   +1 more source

Leveraging Personal Navigation Assistant Systems Using Automated Social Media Traffic Reporting

open access: yes, 2020
Modern urbanization is demanding smarter technologies to improve a variety of applications in intelligent transportation systems to relieve the increasing amount of vehicular traffic congestion and incidents.
Ghazzai, Hakim   +2 more
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

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