Results 41 to 50 of about 552,532 (299)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Functional Characterization of the Saccharomyces cerevisiae Equilibrative Nucleoside Transporter 1 (ScENT1)

Molecules, 2018
Equilibrative nucleoside transporters (ENTs) are polytopic membrane transporters responsible for the translocation of nucleosides, nucleobases—to a lesser extent—and nucleoside analog therapeutics across cellular membranes.
Rebba C. Boswell-Casteel, Jennifer M. Johnson, Franklin A. Hays   +2 more
doaj   +1 more source

Cadmium Accumulation in Cereal Crops and Tobacco: A Review

Agronomy, 2022
Cadmium (Cd) is a toxic heavy metal with no known biological function in plants and one of the most toxic substances released into the environment. Crops, such as rice, maize, wheat and tobacco are the major sources of Cd for humans. Cd toxicity inhibits
Shineng Mei, Kaina Lin, Darron V. Williams, Yang Liu, Huaxin Dai, Fangbin Cao   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Effect of energy sources and levels on caecal microbial population, jejunal morphology, gene expression of jejunal transporters (sglt1, fabp) and performance of broilers under heat stress [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017
The present study was conducted to evaluate the effects of energy sources and levels on microbial population, jejunal morphology, gene expression of glucose transporter (SGLT1), fatty acid binding protein (FABP) and performance in broilers under heat ...
GHAHREMANI A, SADEGHI AA, HESARAKI S, CHAMANI M, SHAWRANG P   +4 more
doaj   +1 more source

Response and Tolerance of Macleaya cordata to Excess Zinc Based on Transcriptome and Proteome Patterns

Plants, 2023
Macleaya cordata is a dominant plant of mine tailings and a zinc (Zn) accumulator with high Zn tolerance. In this study, M. cordata seedlings cultured in Hoagland solution were treated with 200 μmol·L−1 of Zn for 1 day or 7 days, and then, their leaves ...
Hongxiao Zhang, Linfeng Hu, Xinlong Du, Assar Ali Shah, Baseer Ahmad, Liming Yang, Zhiying Mu   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Prescription Advice Based on Data of Drug-Drug-Gene Interaction of Patients with Polypharmacy

Pharmacogenomics and Personalized Medicine, 2022
Sandro Salamone,1 Sara Spirito,2 Maurizio Simmaco,2 Marius Unger,1 Saskia Preissner,3 Björn-Oliver Gohlke,1 Andreas Eckert,1 Robert Preissner1 1Science-IT and Institute of Physiology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie ...
Salamone S, Spirito S, Simmaco M, Unger M, Preissner S, Gohlke BO, Eckert A, Preissner R   +7 more
doaj  

Molecular Characteristics of the Conserved Aspergillus nidulans Transcription Factor Mac1 and Its Functions in Response to Copper Starvation

mSphere, 2019
Copper (Cu) is an essential trace element in all organisms, and Cu acquisition during periods of starvation is important for cell survival and proliferation.
Zhendong Cai, Wenlong Du, Lianhong Liu, Daodong Pan, Ling Lu   +4 more
doaj   +1 more source