Results 41 to 50 of about 180,512 (273)

Directed Chaotic Transport in Hamiltonian Ratchets [PDF]

open access: yesPhys. Rev. E 71 (2005) 026228., 2004
We present a comprehensive account of directed transport in one-dimensional Hamiltonian systems with spatial and temporal periodicity. They can be considered as Hamiltonian ratchets in the sense that ensembles of particles can show directed ballistic transport in the absence of an average force. We discuss general conditions for such directed transport,
arxiv   +1 more source

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

A Node-Expressed Transporter OsCCX2 Is Involved in Grain Cadmium Accumulation of Rice

open access: yesFrontiers in Plant Science, 2018
Excessive cadmium (Cd) accumulation in grains of rice (Oryza sativa L.) is a risk to food security. The transporters in the nodes of rice are involved in the distribution of mineral elements including toxic elements to different tissues such as grains ...
Xiaohua Hao   +12 more
doaj   +1 more source

Comparison of transport map generated by heat flow interpolation and the optimal transport Brenier map [PDF]

open access: yes, 2017
This note shows that the non-expansive transport map constructed by Y.-H. Kim and E. Milman using heat flow interpolation is in general different from the optimal transport Brenier map.
arxiv   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Modulation of Glycinergic Neurotransmission may Contribute to the Analgesic Effects of Propacetamol

open access: yesBiomolecules, 2021
Treating neuropathic pain remains challenging, and therefore new pharmacological strategies are urgently required. Here, the enhancement of glycinergic neurotransmission by either facilitating glycine receptors (GlyR) or inhibiting glycine transporter ...
Lukas Barsch   +3 more
doaj   +1 more source

Transport in three-dimensional topological insulators: theory and experiment [PDF]

open access: yesPhysica E 44, 860 (2012), 2011
This article reviews recent theoretical and experimental work on transport due to the surface states of three-dimensional topological insulators. The theoretical focus is on longitudinal transport in the presence of an electric field, including Boltzmann transport, quantum corrections and weak localization, as well as longitudinal and Hall transport in
arxiv   +1 more source

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

Multiple Targeting Approaches on Histamine H3 Receptor Antagonists

open access: yesFrontiers in Neuroscience, 2016
With the very recent market approval of pitolisant (Wakix®), the interest in clinical applications of novel multifunctional histamine H3 receptor antagonists has clearly increased. Since histamine H3 receptor antagonists in clinical development have been
Mohammad eKhanfar   +5 more
doaj   +1 more source

Untargeted Metabolomics Uncovers the Essential Lysine Transporter in Toxoplasma gondii

open access: yesMetabolites, 2021
Apicomplexan parasites are responsible for devastating diseases, including malaria, toxoplasmosis, and cryptosporidiosis. Current treatments are limited by emerging resistance to, as well as the high cost and toxicity of existing drugs.
Joachim Kloehn   +4 more
doaj   +1 more source

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