Results 71 to 80 of about 43,628 (282)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Finanzielle Folgen des Schwarzfahrens

open access: yessui-generis
Wer ohne gültigen Fahrschein öffentliche Verkehrsbetriebe benutzt, hat den eigentlichen Fahrpreis und den sog. Zuschlag zu bezahlen. Wer dies wiederholt tut, muss auch noch eine Staffelungsgebühr entrichten. Daneben ist auch eine strafrechtliche Ahndung
Luca Schoop
doaj   +1 more source

La situation financière des transports publics urbains est-elle « durable » ? [PDF]

open access: yes
L'analyse du financement des transports publics urbains montre depuis de nombreuses années une croissance de la contribution des collectivités publiques, malgré les efforts de développement de l'offre pour en accroître l'usage.
Bruno Faivre D'Arcier
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

EU Neighbourhood policy: implications for public services and trade unions [PDF]

open access: yes, 2006
The EU Neighbourhood policy creates pressures to liberalise and privatise public services.
Hall, David
core  

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