Results 51 to 60 of about 1,813,007 (299)
Transposable element pangenome code and data
, 2022 Code and data for creating transposable element pangenome graph, genotyping samples and summarising the ...
Guillaume Bourque +2 more
core +1 more source
Tools and best practices for retrotransposon analysis using high-throughput sequencing data
Mobile DNA, 2019 Background Sequencing technologies give access to a precise picture of the molecular mechanisms acting upon genome regulation. One of the biggest technical challenges with sequencing data is to map millions of reads to a reference genome. This problem is
Aurélie Teissandier +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
TARP: Transposable Element Assembly Remapping Pipeline [PDF]
, 2020 Transposable elements are prolific throughout plant genomes and while originally regarded as nothing more than genetic parasites increasing number of studies have shown these elements to contribute significantly to the phenotypes of many significant ...
Holleman, Ethan
core +1 more source
Genome Biology, 2021 Background Variation in gene expression underlies interindividual variability in relevant traits including immune response. However, the genetic variation responsible for these gene expression changes remains largely unknown.
Anna Ullastres +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Association analysis of repetitive elements and R-loop formation across species
Mobile DNA, 2021 Background Although recent studies have revealed the genome-wide distribution of R-loops, our understanding of R-loop formation is still limited. Genomes are known to have a large number of repetitive elements.
Chao Zeng +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Gene regulatory innovations from transposable elements in primate cerebellum development
Nature CommunicationsTransposable elements are hypothesized to have driven gene regulatory innovation, yet their contributions to primate brain development at the cell type level remain underexplored.
Tetsuya Yamada +3 more
doaj +1 more source
A specific insertion of a solo-LTR characterizes the Y-chromosome of
BMC Research Notes, 2010 Background Relatively few species of flowering plants are dioecious and even fewer are known to have sex chromosomes. Current theory posits that homomorphic sex chromosomes, such as found in Bryonia dioica (Cucurbitaceae), offer insight into the early ...
Renner Susanne S +2 more
doaj +1 more source