Results 61 to 70 of about 2,609,081 (310)
A transposable element insertion is associated with an alternative life history strategy
Nature Communications, 2019 Tradeoffs affect resource allocation during development and result in fitness consequences that drive the evolution of life history strategies. Yet despite their importance, we know little about the mechanisms underlying life history tradeoffs.
A. Woronik +10 more
semanticscholar +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
, 2012 PubMed ID: 23185607This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Chase Mark W. +34 more
core +1 more source
Transposable elements and psychiatric disorders
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2014 Transposable Elements (TEs) or transposons are low‐complexity elements (e.g., LINEs, SINEs, SVAs, and HERVs) that make up to two‐thirds of the human genome. There is mounting evidence that TEs play an essential role in genomic architecture and regulation related to both normal function and disease states.
G. Guffanti +6 more
openaire +2 more sources
Asexual reproduction reduces transposable element load in experimental yeast populations
eLife, 2019 Theory predicts that sexual reproduction can either facilitate or restrain transposable element (TE) accumulation by providing TEs with a means of spreading to all individuals in a population, versus facilitating TE load reduction via purifying selection.
Jens Bast +4 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Miniature transposable sequences are frequently mobilized in the bacterial plant pathogen Pseudomonas syringae pv. phaseolicola [PDF]
, 2011 Mobile genetic elements are widespread in Pseudomonas syringae, and often associate with virulence genes. Genome reannotation of the model bean pathogen P. syringae pv.
Murillo, Jesús +23 more
core +1 more source
Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source
Enrichment scores for individual complex repeat and transposable element families.
, 2022 Normalized enrichment scores of the target protein over no-tag control (in RPM) for the complex satellite and transposable element enriched in HipHop and HOAP. (CSV)
Tao Chen (75911) +8 more
core +1 more source
RepetDB: a unified resource for transposable element references
Mobile DNA, 2019 Thanks to their ability to move around and replicate within genomes, transposable elements (TEs) are perhaps the most important contributors to genome plasticity and evolution.
J. Amselem +11 more
semanticscholar +1 more source