Results 21 to 30 of about 65,487 (217)

Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development

Nature Communications, 2023
The contribution of transposable elements and endogenous retroviruses to renal fibroinflammation is currently unknown. Here, the authors comprehensively profile the expression of transposable elements and endogenous retroviruses (ERVs) in kidneys of ...
Poonam Dhillon, Kelly Ann Mulholland, Hailong Hu, Jihwan Park, Xin Sheng, Amin Abedini, Hongbo Liu, Allison Vassalotti, Junnan Wu, Katalin Susztak   +9 more
doaj   +1 more source

Transposable elements in TDP-43-mediated neurodegenerative disorders. [PDF]

PLoS ONE, 2012
Elevated expression of specific transposable elements (TEs) has been observed in several neurodegenerative disorders. TEs also can be active during normal neurogenesis.
Wanhe Li, Ying Jin, Lisa Prazak, Molly Hammell, Josh Dubnau   +4 more
doaj   +1 more source

Evolvability, epigenetics and transposable elements

Biomolecular Concepts, 2011
Evolvability can be defined as the capacity of an individual to evolve and thus to capture adaptive mutations. Transposable elements (TE) are an important source of mutations in organisms.
Fablet Marie, Vieira Cristina
doaj   +1 more source

Involvement of transposable elements in neurogenesis

Вавиловский журнал генетики и селекции, 2020
The article is about the role of transposons in the regulation of functioning of neuronal stem cells and mature neurons of the human brain. Starting from the first division of the zygote, embryonic development is governed by regular activations of ...
R. N. Mustafin, E. K. Khusnutdinova
doaj   +1 more source

Transposable elements as essential elements in the control of gene expression

Mobile DNA, 2023
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile elements, make up a significant portion of the genomes of higher animals.
Alemu Gebrie
doaj   +1 more source

Chromosome-level comparative genomics and host-specific fungal transcriptomics uncover adaptive virulence strategies in the sugarcane smut pathogen

BMC Genomics
Background Sporisorium scitamineum is the causal agent of sugarcane smut, affecting global sugarcane production. Despite advances in smut genomics, the relationships between fungal genetic diversity, host adaptation, and virulence remain elusive. Methods
Pedro Fernando Vilanova, Lucas Mitsuo Taniguti, Marcella Ferreira, Thaís Carolina da Silva Dal’Sasso, Gustavo Schiavone Crestana, Lâina da Silva de Oliveira, Renato Gustavo Hoffmann Bombardelli, Tatiana Caroline Pisetta, Paula Turini, João Paulo Kitajima, Silvana Creste, Luis Eduardo Aranha Camargo, Marie-Anne Van Sluys, Claudia Barros Monteiro-Vitorello   +13 more
doaj   +1 more source

Regulatory regions in natural transposable element insertions drive interindividual differences in response to immune challenges in Drosophila

Genome Biology, 2021
Background Variation in gene expression underlies interindividual variability in relevant traits including immune response. However, the genetic variation responsible for these gene expression changes remains largely unknown.
Anna Ullastres, Miriam Merenciano, Josefa González   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Characterization of active transposable elements and their new insertions in tuber propagated greater yam (Dioscorea alata)

BMC Genomics
Background Greater yam is a key staple crop grown in tropical and subtropical regions, while its asexual propagation mode had led to non-flowering mutations. How transposable elements contribute to its genetic variations is rarely analyzed.
Sajjad Ali Panhwar, Dandan Wang, Fanhui Lin, Ying Wang, Mengli Liu, Runan Chen, Yonglan Huang, Wenqiang Wu, Dongyi Huang, Yong Xiao, Wei Xia   +10 more
doaj   +1 more source

Changes in global gene expression in response to chemical and genetic perturbation of chromatin structure. [PDF]

PLoS ONE, 2011
DNA methylation is important for controlling gene expression in all eukaryotes. Microarray analysis of mutant and chemically-treated Arabidopsis thaliana seedlings with reduced DNA methylation revealed an altered gene expression profile after treatment ...
Karen Hudson, Song Luo, Nicole Hagemann, Daphne Preuss   +3 more
doaj   +1 more source