Results 21 to 30 of about 67,153 (262)

Transposable Elements: No More 'Junk DNA' [PDF]

Genomics & Informatics, 2012
Since the advent of whole-genome sequencing, transposable elements (TEs), just thought to be 'junk' DNA, have been noticed because of their numerous copies in various eukaryotic genomes.
Yun-Ji Kim, Jungnam Lee, Kyudong Han
doaj   +1 more source

Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males

Nature Communications, 2020
Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates ...
Kevin H.-C. Wei, Lauren Gibilisco, Doris Bachtrog   +2 more
doaj   +1 more source

Host-parasite relationships in the genome

BMC Biology, 2011
Transposable elements are best interpreted as genomic parasites, proliferating in genomes through their over-replication relative to the rest of the genome. A new study examining correlations across Drosophila species between transposable element numbers
Brookfield John FY
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Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development

Nature Communications, 2023
The contribution of transposable elements and endogenous retroviruses to renal fibroinflammation is currently unknown. Here, the authors comprehensively profile the expression of transposable elements and endogenous retroviruses (ERVs) in kidneys of ...
Poonam Dhillon, Kelly Ann Mulholland, Hailong Hu, Jihwan Park, Xin Sheng, Amin Abedini, Hongbo Liu, Allison Vassalotti, Junnan Wu, Katalin Susztak   +9 more
doaj   +1 more source

Transposable elements in TDP-43-mediated neurodegenerative disorders. [PDF]

PLoS ONE, 2012
Elevated expression of specific transposable elements (TEs) has been observed in several neurodegenerative disorders. TEs also can be active during normal neurogenesis.
Wanhe Li, Ying Jin, Lisa Prazak, Molly Hammell, Josh Dubnau   +4 more
doaj   +1 more source

Evolvability, epigenetics and transposable elements

Biomolecular Concepts, 2011
Evolvability can be defined as the capacity of an individual to evolve and thus to capture adaptive mutations. Transposable elements (TE) are an important source of mutations in organisms.
Fablet Marie, Vieira Cristina
doaj   +1 more source

Transposable elements as essential elements in the control of gene expression

Mobile DNA, 2023
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile elements, make up a significant portion of the genomes of higher animals.
Alemu Gebrie
doaj   +1 more source

Chromosome-level comparative genomics and host-specific fungal transcriptomics uncover adaptive virulence strategies in the sugarcane smut pathogen

BMC Genomics
Background Sporisorium scitamineum is the causal agent of sugarcane smut, affecting global sugarcane production. Despite advances in smut genomics, the relationships between fungal genetic diversity, host adaptation, and virulence remain elusive. Methods
Pedro Fernando Vilanova, Lucas Mitsuo Taniguti, Marcella Ferreira, Thaís Carolina da Silva Dal’Sasso, Gustavo Schiavone Crestana, Lâina da Silva de Oliveira, Renato Gustavo Hoffmann Bombardelli, Tatiana Caroline Pisetta, Paula Turini, João Paulo Kitajima, Silvana Creste, Luis Eduardo Aranha Camargo, Marie-Anne Van Sluys, Claudia Barros Monteiro-Vitorello   +13 more
doaj   +1 more source

Involvement of transposable elements in neurogenesis

Вавиловский журнал генетики и селекции, 2020
The article is about the role of transposons in the regulation of functioning of neuronal stem cells and mature neurons of the human brain. Starting from the first division of the zygote, embryonic development is governed by regular activations of ...
R. N. Mustafin, E. K. Khusnutdinova
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source