Results 61 to 70 of about 2,835,830 (298)
Nature CommunicationsTransposable elements are abundant in the human genome and have been increasingly recognized as sources of alternative promoters. Yet, the extent of their transcriptional activity in human tissues and the features that govern their regulatory potential ...
Ya Zhang +3 more
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Transposable elements and psychiatric disorders
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2014 Transposable Elements (TEs) or transposons are low‐complexity elements (e.g., LINEs, SINEs, SVAs, and HERVs) that make up to two‐thirds of the human genome. There is mounting evidence that TEs play an essential role in genomic architecture and regulation related to both normal function and disease states.
G. Guffanti +6 more
openaire +2 more sources
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
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Novel transposable elements from
BMC Genomics, 2011 Background Transposable elements (TEs) are DNA sequences, present in the genome of most eukaryotic organisms that hold the key characteristic of being able to mobilize and increase their copy number within chromosomes.
Ribeiro José MC +2 more
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Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
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Prokaryotic Transposable Elements
Prokaryotes have provided an abundance of transposable elements (TEs), which have greatly contributed to our present understanding of the importance of TE in remodeling their host genomes and regulating gene expression, and have been key to our present ...
Varani, Alessandro M. [UNESP] +2 more
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Genome BiologyBackground Ticks are obligate blood-feeding parasites associated with a huge diversity of diseases globally. The hard tick Ixodes ricinus is the key vector of Lyme borreliosis and tick-borne encephalitis in Western Eurasia.
Isobel Ronai +9 more
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Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Transposable elements within TRIM DHS
, 2016 This files showed the transposable elements that overlapped with TRIM haDHSs and conversed DHSs and their detailed information. The first three columns represented the position of DHS, the fourth to sixth columns represented the position of transposable ...
He, Dan-Dan +11 more
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Repeats in the transcribed regions: comprehensive characterization and comparison of Citrus spp. [PDF]
Frontiers of Agricultural Science and Engineering, 2017 A large number of expressed sequences tags are available for Citrus spp., which provides an opportunity to understand genomic organization of the transcribed regions.
Manosh Kumar BISWAS, Christoph MAYER, Xiuxin DENG
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