Results 71 to 80 of about 153,753 (318)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Length enumeration of fully commutative elements in finite and affine Coxeter groups [PDF]
J. Algebra, 513 (2018) 466-515, 2016 An element w of a Coxeter group W is said to be fully commutative, if any reduced expression of w can be obtained from any other by transposing adjacent pairs of generators. These elements were described in 1996 by Stembridge in the case of finite irreducible groups, and more recently by Biagioli, Jouhet and Nadeau (BJN) in the affine cases.
arxiv +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, EarlyView.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Background The use of deep learning‐based auto‐contouring algorithms in various treatment planning services is increasingly common. There is a notable deficit of commercially or publicly available models trained on large or diverse datasets containing high‐dose‐rate (HDR) brachytherapy treatment scans, leading to poor performance on images ...
Andrew J. Krupien +8 more
wiley +1 more source
A retrotransposon-based-strategy for the assessment of genetic and epigenetic stability of oil palm embryogenic suspensions [PDF]
, 2012 Clonal regenerants of oil palm (Elaeis guineensis Jacq) can display a detrimental variant phenotype called mantled which affects the floral morphology of adult palms thus lowering oil yields in clonal offspring.
Beulé, Thierry +7 more
core
Modulating signaling networks by CRISPR/Cas9-mediated transposable element insertion [PDF]
, 2018 In a recent past, transposable elements (TEs) were referred to as selfish genetic components only capable of copying themselves with the aim of increasing the odds of being inherited.
A Bolotin +76 more
core +1 more source
Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron +3 more
wiley +1 more source
Insects, 2020 The cotton bollworm Helicoverpa armigera Hübner (Lepidoptera: Noctuidae) is an important pest of many crops that has developed resistance to almost all groups of insecticides used for its management.
Khouloud KLAI +9 more
doaj +1 more source
On orders of elements of finite almost simple groups with linear or unitary socle [PDF]
J. Group Theory 20 (2017), 1191-1222, 2016 We say that a finite almost simple $G$ with socle $S$ is admissible (with respect to the spectrum) if $G$ and $S$ have the same sets of orders of elements. Let $L$ be a finite simple linear or unitary group of dimension at least three over a field of odd characteristic. We describe admissible almost simple groups with socle $L$.
arxiv +1 more source
Cerebello‐Prefrontal Connectivity Underlying Cognitive Dysfunction in Spinocerebellar Ataxia Type 2
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 2 (SCA2) is a hereditary cerebellar degenerative disorder, with motor and cognitive symptoms. The constellation of cognitive symptoms due to cerebellar degeneration is named cerebellar cognitive affective syndrome (CCAS), which has increasingly been recognized to profoundly impact patients' quality of life;
Ami Kumar +7 more
wiley +1 more source