Results 121 to 130 of about 2,238 (250)
Problems of operationalization and data in EU compliance research [PDF]
Substantial theoretical, conceptual and empirical advances have been made in research on the implementation of EU policies during recent years. However, our findings have remained ambivalent and our theoretical insights disparate. It therefore seems high
Falkner, Gerda, Hartlapp, Miriam
core
Structure and Stability of Tn9-mediated Cointegrates: Evidence of Two Pathways of Transposition
, 1982 We have measured the frequency of Tn9 transposition and cointegrate formation in several different ways and have examined the stability of the cointegrates. We have also physically analyzed the structure of 40 independently derived cointegrate molecules.
Chandler, Michael, Galas, David J.
core +1 more source
Energy Conversion and Management: XRenewable Energy Communities (RECs) have been clearly defined in the EU Renewable Energy Directive (RED) II (Directive 2018/2001) contained within the Clean Energy Package (CEP).
G.U. Magni +4 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Ensemble Flood Forecasting Using Transposition of NWP Rainfall Fields Considering Orographic Rainfall [PDF]
, 2014 The use of meteorological ensembles to produce sets of hydrological predictions has increased the ability to issue flood warnings. However, the spatial scale of a hydrological domain is still much finer than that of a meteorological model, and Numerical ...
KIM, Sunmin +3 more
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
TEACHER TRAINING AND PRACTICE OF CHEMISTRY: a study of the didactic transposition of atomic models.
, 2010 This Study aimed to investigate how was the didactic transposition of atomic models in the first degree course in Chemistry, Sergipe in Federal University and two schools in the Network State Public High School in Aracaju-SE.
Santana, Rafael de Jesus
core
APPENDIX: A Model for Mu Transposition
Cold Spring Harbor Symposia on Quantitative Biology, 1981 R. M. Harshey, A. I. Bukhari
openaire +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source