Results 141 to 150 of about 119,289 (331)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Design and Construction of Inductive Compensation for Extra-High-Voltage Transmission Line Models of Physical Laboratory of Electric Power Systems

Engineering Proceedings
The implementation of inductive compensation in the two-scale models of the extra-high-voltage transmission line, without and with transposition, of the Physical Laboratory of Electric Power Systems (PLEPS) is presented.
Anderson Anrrango Delgado, Anghelo Navarrete Cumbal, Jesús Játiva Ibarra   +2 more
doaj   +1 more source

Transposable Element activation promotes neurodegeneration in a Drosophila model of Huntington’s disease

, 2020
Assunta Maria Casale, Francesco Liguori, Federico Ansaloni, Ugo Cappucci, Sara Finaurini, Giovanni Spirito, Francesca Persichetti, Remo Sanges, Stefano Gustincich, Lucia Piacentini   +9 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Advancing Machine Learning-Based Streamflow Prediction Through Event Greedy Selection, Asymmetric Loss Function, and Rainfall Forecasting Uncertainty

Applied Sciences
This paper advances machine learning (ML)-based streamflow prediction by strategically selecting rainfall events, introducing a new loss function, and addressing rainfall forecast uncertainties. Focusing on the Iowa River Basin, we applied the stochastic
Soheyla Tofighi, Faruk Gurbuz, Ricardo Mantilla, Shaoping Xiao   +3 more
doaj   +1 more source

MATES: a deep learning-based model for locus-specific quantification of transposable elements in single cell [PDF]

Ruohan Wang, Yumin Zheng, Zijian Zhang, Kailu Song, Erxi Wu, Xiaopeng Zhu, Tao Wu, Jun Ding   +7 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

On Topological Indices for Swapped Networks Modeled by Optical Transpose Interconnection System [PDF]

, 2020
Nida Zahra, Muhammad Ibrahim, Muhammad Kamran Siddiqui   +2 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Sequence Analysis at IS1 Insertion Sites: Models for Transposition

Cold Spring Harbor Symposia on Quantitative Biology, 1979
N D, Grindley, D J, Sherratt
openaire   +2 more sources