Results 211 to 220 of about 111,214 (295)

Mobilization of <i>bla</i>_VIM genes via the Tn6292 transposon among carbapenem-resistant <i>Enterobacter cloacae</i> complex isolates from colonized patients in a Spanish hospital. [PDF]

Microbiol Spectr
Ríos E, Rodríguez-Avial I, López R, Martínez M, González F, Delgado-Iribarren A, Culebras E.   +6 more
europepmc   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Bacteriophage genome-wide transposon mutagenesis. [PDF]

Cell
Chan A, Yee WX, Mozumdar D, Kokontis C, Rojas-Montero M, Liu M, Yang Y, Yuping L, Bondy-Denomy J.   +8 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, Volume 600, Issue 17, Page 2579-2614, September 2026.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Novel transposon Tn<i>8026</i> contributes to the global spread of transmissible linezolid resistance in <i>Enterococcus</i> via a linear plasmid. [PDF]

Microb Genom
Hall MB, Xue Y, Lee TSE, Herring E, Hume J, Wick RR, Kidd T, Runnegar N, Harris PNA, Graves B, Roberts LW.   +10 more
europepmc   +1 more source

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, Volume 13, Issue 49, 3 September 2026.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

Tissue-specific DNA repair strategies underlie apparent high transposon activity in the Caenorhabditis elegans soma. [PDF]

G3 (Bethesda)
Chang C, Lowe DD, Kennedy S.
europepmc   +1 more source

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan, Zhe Gao, Yingxuan Qi, Yang Zhang, Xuhui Tian, Pengpeng Zhao, Xu Feng, Qunxin She   +7 more
wiley   +1 more source

The GspCD-dependent type II secretion system promotes necrotizing soft tissue infection caused by <i>Aeromonas hydrophila</i>. [PDF]

Front Cell Infect Microbiol
Tonosaki Y, Yamazaki K, Owada S, Yamaguchi K, Kashimoto T.   +4 more
europepmc   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, Volume 13, Issue 50, 7 September 2026.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source