Asking the 5 W's for designing next‐generation bioprocessing
Abstract Biotechnology is expanding beyond traditional, centralized fermentation and toward next‐generation bioprocessing paradigms that emphasize flexible deployment outside the laboratory with application‐specific performance. However, many bioprocesses fail to translate beyond proof‐of‐concept into industrially viable systems because early design ...
Sangdo Yook +4 more
wiley +1 more source
Genomic Diversity and Extended-Spectrum <i>β</i>-Lactamase Gene Contexts of Community Resident-Carried <i>Escherichia coli</i> in Ecuador. [PDF]
Azumah JD +6 more
europepmc +1 more source
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew +8 more
wiley +1 more source
Transposon insertion sequencing identifies novel genes involved in product synthesis in gas-fermenting <i>Clostridium ljungdahlii</i>. [PDF]
Zhang Z +8 more
europepmc +1 more source
TMEM106B is a selective modulator of TDP‐43 pathology in Alzheimer's disease
Abstract INTRODUCTION Co‐pathologies – including Lewy body, vascular, and TDP‐43 lesions – are common in Alzheimer's disease (AD), contributing to its clinical and pathological heterogeneity. Genetic risk factors may drive mixed pathology presentation, but their influence on the development of specific co‐pathologies remains unclear.
Madison M. Reeves +21 more
wiley +1 more source
A reference genome for cultured Drosophila ovarian somatic cells enables studies of transposon and piRNA biology. [PDF]
Handler D, Brennecke J.
europepmc +1 more source
Abstract INTRODUCTION Intrinsic functional connectivity network abnormalities in C9orf72 hexanucleotide repeat expansion carriers emerge during the asymptomatic phase, yet longitudinal studies remain limited. We examined cross‐sectional abnormalities and longitudinal connectivity changes across clinical stages.
Liwen Zhang +23 more
wiley +1 more source
Integrated analysis of transposon insertion sequencing and pangenome reveals core and lineage-specific essential genes in <i>Mycobacterium avium</i> subsp. <i>hominissuis</i>. [PDF]
Sawai K +9 more
europepmc +1 more source
Telomere-to-telomere genome assembly of Oryza australiensis reveals transposon-driven centromere repositioning and shared EE-DD ancestry. [PDF]
Bao Y +11 more
europepmc +1 more source
Mutations that confer resistance to sodium azide affect the levels of two physiological isoforms of SecA in <i>Escherichia coli</i>. [PDF]
Jiang C +5 more
europepmc +1 more source

