Results 251 to 260 of about 111,214 (295)
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CRISPR transposons on the move
Cell Host & Microbe, 2021CRISPR transposons (CASTs) represent unique mobile genetic elements that co-opted CRISPR-Cas immune systems for RNA-guided DNA transposition. However, CAST-encoded CRISPR arrays rarely match the CAST's chromosomal location. A recent publication in Cell helps resolve this paradox by revealing CRISPR-array-independent mechanisms of chromosomal homing ...
Ioannis, Mougiakos, Chase L, Beisel
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Trends in Plant Science, 2002
Mutator (Mu) element insertion has become the main way of mutating and cloning maize genes, but we are only beginning to understand how this transposon system is regulated. Mu elements are under tight developmental control and are subject to a form of epigenetic regulation that shares some features with the regulation of paramutable maize genes.
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Mutator (Mu) element insertion has become the main way of mutating and cloning maize genes, but we are only beginning to understand how this transposon system is regulated. Mu elements are under tight developmental control and are subject to a form of epigenetic regulation that shares some features with the regulation of paramutable maize genes.
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2014
Transposon-based mutagenesis of bacterial genomes is a powerful method to identify genetic elements that control specific phenotypes. The most frequently used transposon tools in Pseudomonas aeruginosa are based either on Himar1 mariner or Tn5 transposases, both of which have been used to generate nonredundant mutant libraries in P. aeruginosa. Here we
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Transposon-based mutagenesis of bacterial genomes is a powerful method to identify genetic elements that control specific phenotypes. The most frequently used transposon tools in Pseudomonas aeruginosa are based either on Himar1 mariner or Tn5 transposases, both of which have been used to generate nonredundant mutant libraries in P. aeruginosa. Here we
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Science (New York, N.Y.), 2010
Ac (Activator) is the first autonomous transposon described by McClintock. Its ability to create DSBs (Double Strand Breaks) makes it a powerful mutagen. In the presence of the Ac transposase, its non-autonomous Ds (Dissociation) counterparts are just as mutagenic.
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Ac (Activator) is the first autonomous transposon described by McClintock. Its ability to create DSBs (Double Strand Breaks) makes it a powerful mutagen. In the presence of the Ac transposase, its non-autonomous Ds (Dissociation) counterparts are just as mutagenic.
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Structural basis for the assembly of the type V CRISPR-associated transposon complex
Cell, 2022Christelle Chanez +2 more
exaly