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Heterogeneous Lineages of DNA Transposons Encode a TET/JBP Dioxygenase in Fungi [PDF]

open access: yesBiology
Epigenetic DNA modification is a key component of the defense system against invading nucleic acids such as transposons. TET/JBP dioxygenases oxidize 5-methylcytosine and lead to its replacement by cytosine in mammals.
Kenji K. Kojima
doaj   +2 more sources

Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification. [PDF]

open access: yesPLoS Biology, 2003
Heritable, but reversible, changes in transposable element activity were first observed in maize by Barbara McClintock in the 1950s. More recently, transposon silencing has been associated with DNA methylation, histone H3 lysine-9 methylation (H3mK9 ...
Zachary Lippman   +4 more
doaj   +3 more sources

Transposons disrupt genomic stability and trigger cancers [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
Transposons (TEs) are genetic elements that can change their positions within genome. They cause transcriptional activation or repression by inserting into regulatory elements of related genes or by modulating epigenetic modifications on regulatory ...
Weixia Dong   +7 more
doaj   +2 more sources

Mobilome of Environmental Isolates of Clostridioides difficile [PDF]

open access: yesAntibiotics
Background/Objectives: Clostridioides difficile is a “One Health” pathogen and a cause of antibiotics-associated diarrhea and pseudomembranous colitis. Mobile genetic elements (MGEs) have been documented in the genomes of clinical C.
Khald Blau, Claudia Gallert
doaj   +2 more sources

Flax transposons: unraveling their impact on domestication and agronomic trait variation [PDF]

open access: yesВавиловский журнал генетики и селекции
Flax is an important agricultural crop with multifunctional uses. Diversified breeding for oil content in seeds and fiber in stems has led to the emergence of two morphotypes – fiber flax and oilseed flax.
M. A. Duk   +5 more
doaj   +2 more sources

The first discovery of Tc1 transposons in yeast

open access: yesFrontiers in Microbiology, 2023
BackgroundIdentification of transposons without close homologs is still a difficult task. IS630/Tc1/mariner transposons, classified into a superfamily, are probably the most widespread DNA transposons in nature.
Jia Chang   +10 more
doaj   +1 more source

Genetic characterisation of antibiotic resistance transposons Tn6608 and Tn6609 isolated from clinical Pseudomonas strains in Cyprus

open access: yesJournal of Global Antimicrobial Resistance, 2021
: Objectives: Antibiotic therapy for Pseudomonas infections is becoming increasingly difficult. In this study, the transposons from two multidrug-resistant (MDR) clinical Pseudomonas strains containing related transposons responsible for giving rise to ...
Vaheesan Rajabal   +6 more
doaj   +1 more source

Introduction of Plant Transposon Annotation for Beginners

open access: yesBiology, 2023
Transposons are mobile DNA sequences that contribute large fractions of many plant genomes. They provide exclusive resources for tracking gene and genome evolution and for developing molecular tools for basic and applied research.
Dongying Gao
doaj   +1 more source

Cargo Genes of Tn7-Like Transposons Comprise an Enormous Diversity of Defense Systems, Mobile Genetic Elements, and Antibiotic Resistance Genes

open access: yesmBio, 2021
Transposition is a major mechanism of horizontal gene mobility in prokaryotes. However, exploration of the genes mobilized by transposons (cargo) is hampered by the difficulty in delineating integrated transposons from their surrounding genetic context ...
Sean Benler   +5 more
doaj   +1 more source

Evolution of piggyBac Transposons in Apoidea

open access: yesInsects, 2023
In this study, we investigated the presence of piggyBac (PB) transposons in 44 bee genomes from the Apoidea order, which is a superfamily within the Hymenoptera, which includes a large number of bee species crucial for pollination.
Xueyuan Li   +9 more
doaj   +1 more source

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