Results 141 to 150 of about 76,361 (277)

The transferable resistome of biosolids—plasmid sequencing reveals carriage of clinically relevant antibiotic resistance genes

open access: yesmBio
Biosolids, widely used as organic fertilizers due to their high nutrient content, are significant reservoirs for antimicrobial-resistant bacteria (ARB) carrying transferable antimicrobial resistance genes (ARGs).
Kristin Hauschild   +11 more
doaj   +1 more source

Comparative Satellitomics in Arowanas (Telostei, Osteoglossiformes) Sheds Light on the Evolution of Ancient Satellite DNAs

open access: yesIntegrative Zoology, EarlyView.
This work focused on arowana fishes (Teleostei, Osteoglossiformes) as a model; their widespread intercontinental distribution and basal phylogenetic position within Teleostei make them a compelling model for evolutionary research, especially in the realm of satDNA molecular evolution. Through the integration of genomic and chromosomal data, we analyzed
Fernando Henrique Santos de Souza   +9 more
wiley   +1 more source

Chromosome‐Level Genome Assemblies of Two Softshell Turtles with ZZ/ZW Provide Insights into TE‐Driven Recombination Suppression in Sex Chromosomes

open access: yesIntegrative Zoology, EarlyView.
This study presents the first genomic identification and characterization of ZW sex chromosomes in two soft‐shelled turtle species through genome assembly and resequencing. We reveal the structural organization of ZW chromosomes, identifying both pseudoautosomal regions (PARs) and differentiated regions.
Jianjun Liu   +9 more
wiley   +1 more source

Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction

open access: yesBrain Pathology, EarlyView.
Canine cognitive dysfunction (CCD) may be a promising model of Alzheimer's disease (AD). To assess AD‐related molecular signatures in CCD, we generated transcriptome data on dog cortex and plasma extracellular vesicles (EVs). CCD‐related transcriptome changes were similar to those in aging/AD humans and were detectable in EVs from the same animals ...
Shelby C. Osburn   +7 more
wiley   +1 more source

Developmental expression of Ap‐Vas proteins in aphids and flies reveals their evolutionary roles in insects

open access: yesInsect Molecular Biology, EarlyView.
Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin   +4 more
wiley   +1 more source

Antibiotic resistance in E. coli isolates from wild-living animals

open access: yesBioingeniøren, 2008
This study indicates that wild-living animals can harbour antibiotic resistant bacteria in their microbial intestinal flora, even if they have not been exposed to selection pressure from the usage of antimicrobial agents.
Jannice Schau Slettemeås   +1 more
doaj  

Genome‐wide and gene‐specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant

open access: yesInsect Molecular Biology, EarlyView.
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro   +4 more
wiley   +1 more source

Auto‐inducible expression of chimeric antigen receptor T cells using the NR4A1 promoter

open access: yesImmunology &Cell Biology, EarlyView.
The NR4A1 promoter is a compact auto‐inducible promoter to drive CAR expression in T cells. Compared with EF1α, or existing synthetic antigen‐inducible promoters, NR4A1 is more compact and ensures that resting CAR T cells express reduced baseline CAR. NR4A1 allows rapid induction upon antigen encounter with reduced T‐cell exhaustion.
Samuel WJ Smith‐Bell   +5 more
wiley   +1 more source

New insights into the putative XX/XY sex chromosomal system in blue‐eyed red‐fin pleco Hypostomus soniae (Siluriformes, Loricariidae)

open access: yesJournal of Fish Biology, EarlyView.
Abstract Blue‐eyed red‐fin pleco Hypostomus soniae (family Loricariidae) presented a putative sex system XX/XY in early stage. Aiming to explore the inter‐populational karyotypic variation and proposed emergence of the XX/XY system, we studied 13 H. soniae individuals (6 males, 7 females) from the Tapajós River.
Luan Aércio Melo Maciel   +6 more
wiley   +1 more source

Stem microanatomical phenomic uncovers a potential role for ZmLSM2 in regulating maize stem bending strength

open access: yesJournal of Integrative Plant Biology, EarlyView.
Maize ZmLSM2 (U6 small nuclear ribonucleoprotein specific Sm‐like 2) controls maize stem strength by affecting vascular bundle structure. Using advanced computed tomography imaging and artificial intelligence identified key stem traits linked to lodging resistance and developed a predictive model.
Ying Zhang   +14 more
wiley   +1 more source

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