Results 31 to 40 of about 8,150 (120)

The effects of chest drainage on pressure-controlled ventilation

JA Clinical Reports, 2022
Background The use of pressure-controlled ventilation (PCV) for anesthesia management is becoming more commonly used. Chest drainage is commonly performed after thoracic surgery, and the negative pressure it generates might affect the transpulmonary ...
Yuko Matsumoto, Shinju Obara, Takahiro Hakozaki, Tsuyoshi Isosu, Satoki Inoue   +4 more
doaj   +1 more source

The effect of target transpulmonary driving pressure values on mortality in ARDS patients: A retrospective study based on the MIMIC-IV database.

PLoS ONE
BackgroundThis study examined the effect of target transpulmonary driving pressure on mortality in patients with Acute Respiratory Distress Syndrome, assessing how varying levels of transpulmonary driving pressure influence clinical outcomes.MethodsThis ...
Na Liu, Qi Zhang, Huiyong Wang, Renshuang Ding, Xiaoyong Geng, Li Wang, Zhiyong Wang, Mingxing Fang   +7 more
doaj   +1 more source

Understanding cardiopulmonary interactions through esophageal pressure monitoring

Frontiers in Physiology, 2023
Esophageal pressure is the closest estimate of pleural pressure. Changes in esophageal pressure reflect changes in intrathoracic pressure and affect transpulmonary pressure, both of which have multiple effects on right and left ventricular performance ...
Elena Spinelli, Gaetano Scaramuzzo, Douglas Slobod, Tommaso Mauri, Tommaso Mauri   +4 more
doaj   +1 more source

Association Between Delivery Room Continuous Positive Airway Pressure and Neonatal Outcomes in Late Preterm and Term Infants: A Systematic Review and Meta‐Analysis

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective To explore the effects of delivery room continuous positive airway pressure (DR‐CPAP) in late preterm and term infants. Design Systematic review and meta‐analysis. Data Sources Cochrane Library, Embase, Emcare and MEDLINE were searched through March 26, 2025.
Yoxin Chin, Maclean Hill, Arun Sett, Niranjan Thomas, Abdul Razak   +4 more
wiley   +1 more source

Haemodynamic effects of selective venoconstriction with centhaquine in spontaneously breathing patients with mixed hypovolaemic‐vasodilatory shock

Experimental Physiology, EarlyView.
Abstract Circulatory shock remains difficult to manage because fluid resuscitation and catecholamines may exacerbate vascular dysfunction and tissue hypoperfusion. This prospective physiological analysis, embedded within a multicentre phase IV study, examined whether selectively targeting the venous circulation with centhaquine improves circulatory ...
Athanasios Chalkias, Aman Khanna, Krish Vaidya, Dharmesh Shah, Anil Gulati   +4 more
wiley   +1 more source

Effects of inspiratory flow on lung stress, pendelluft, and ventilation heterogeneity in ARDS: a physiological study

Critical Care, 2019
Background High inspiratory flow might damage the lungs by mechanisms not fully understood yet. We hypothesized that increasing inspiratory flow would increase lung stress, ventilation heterogeneity, and pendelluft in ARDS patients undergoing volume ...
Alessandro Santini, Tommaso Mauri, Francesca Dalla Corte, Elena Spinelli, Antonio Pesenti   +4 more
doaj   +1 more source

Determinants of maximal oxygen uptake in highly trained females and males: a mechanistic study of sex differences using advanced invasive methods

The Journal of Physiology, EarlyView.
Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo, Marcos Martin‐Rincon, Bjarne Rud, Joachim Nielsen, Lars Henrik N. Hegg, Andreas V. Kleive, Niels Ørtenblad, Øyvind Sandbakk, Robert Boushel, Hans‐Christer Holmberg, Jose A.L. Calbet, Jostein Hallén   +11 more
wiley   +1 more source

Gas exchange and pulmonary stress variations during SCUBA and breath‐hold diving in open seawater

The Journal of Physiology, EarlyView.
Abstract figure legend Healthy, trained divers were studied before, during and after diving in open seawater with different techniques. SCUBA divers (diving to 15 or 40 m with air; cycling at depth) and breath‐hold divers (BHDs; sled‐assisted dives to 15, 25 or 40 m) underwent underwater and surface arterial blood gas (ABG) sampling.
Matteo Paganini, Tommaso Antonio Giacon, Simona Mrakic‐Sposta, Luca Martani, Danilo Cialoni, Lorenzo Zucchi, Vincenzo Maffei, Rosario Cifali, Mariano Marmo, Enrico M Camporesi, Richard E Moon, Gerardo Bosco   +11 more
wiley   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Mapping the strain-stiffening behavior of the lung and lung cancer at microscale resolution using the crystal ribcage

Frontiers in Network Physiology
Lung diseases such as cancer substantially alter the mechanical properties of the organ with direct impact on the development, progression, diagnosis, and treatment response of diseases.
Robert LeBourdais, Gabrielle N. Grifno, Rohin Banerji, Kathryn Regan, Bela Suki, Hadi T. Nia   +5 more
doaj   +1 more source