Results 51 to 60 of about 8,150 (120)
Prognostic Value of Right Atrial Adverse Remodeling in Patients With Pulmonary Arterial Hypertension
ABSTRACT Assessment of right atrial (RA) structure helps monitor right heart (RH) function, critical for prognosis in pulmonary arterial hypertension (PAH). This study aims to assess the prognostic value of RA adverse remodeling (RAAR) with targeted therapy in PAH. Patients diagnosed with PAH between June 2013 and June 2024 were prospectively recruited.
Ji Zhao +13 more
wiley +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
ABSTRACT Cerebral vasospasm is a major complication of aneurysmal subarachnoid hemorrhage and a key contributor to delayed cerebral ischemia, which remains a leading cause of morbidity despite standard therapy with nimodipine and induced hypertension.
Paul Cardozo Gil +7 more
wiley +1 more source
IntroductionPositive end-expiratory pressure (PEEP) and prone positioning can improve gas exchange by promoting uniform lung aeration. However, elevated ventilation pressures may increase intracranial pressure (ICP) and disrupt cerebral autoregulation ...
Rønnaug Hammervold +16 more
doaj +1 more source
ABSTRACT We present the anesthetic management for a patient with single ventricle Fontan palliation undergoing simultaneous cardiac catheterization and CPAP titration, where the anesthetic ensured the pertinent goals of maintaining patient comfort, simulation of normal sleep, and preservation of physiologic conditions.
Amanda Redding +6 more
wiley +1 more source
PSO exhibited protective effects against CSE‐induced pulmonary inflammation by reducing macrophage and eosinophil infiltration, preventing alveolar destruction, and enhancing antioxidant defense by lowering serum MDA levels in a murine COPD model. These findings support the potential role as a dietary supplement for the prevention or attenuation of ...
Gaewarin Liamvilairat +5 more
wiley +1 more source
MRI for Lung Cancer Management: Any Closer to Clinical Application?
ABSTRACT Management of lung cancer (LC) encompasses screening, diagnosis, staging, radiotherapy planning and guidance, therapy monitoring and surveillance. Across these domains, magnetic resonance imaging (MRI) offers a range of morphological and functional imaging capabilities—including diffusion‐weighted imaging (DWI), dynamic contrast‐enhanced (DCE)
Juergen Biederer +10 more
wiley +1 more source
Cardiopulmonary interaction during spontaneous breathing and mechanical ventilation [PDF]
Cardiopulmonary interaction is a fundamental physiological process during spontaneous breathing, but it is profoundly altered in critically ill patients receiving mechanical ventilation (MV). Positive-pressure ventilation modifies intrathoracic, pleural,
Angel Benjamin Rojas +3 more
doaj +1 more source
We report a life‐threatening recurrent pneumothorax in a polytrauma patient following posterior spinal fixation, triggered by the physiological stress of prone positioning and positive pressure ventilation on a pre‐existing pulmonary contusion. This case highlights the critical risk of early chest tube removal and advocates for maintaining pleural ...
Parisa Mirzaei +2 more
wiley +1 more source
Lung injury promoted by strong inspiratory efforts and breath stacking: impact of ventilation mode
Background Breath stacking, particularly double triggering, is a common patient–ventilator asynchrony during strong inspiratory effort. It can cause excessive tidal volumes and high transpulmonary pressures, contributing to ventilator-induced lung injury
Yasuhiro Norisue +18 more
doaj +1 more source

