Transthyretin (prealbumin) in eye structures and variation of vitreous-transthyretin in diseases.
To evaluate the presence of transthyretin (TTR, prealbumin) a protein which binds retinol to retinol-binding protein in various ocular tissues and to study its quantitative changes in the vitreous humor in various diseases.Estimation of TTR was done by electrophoresis of 10 mg protein in each sample of tears, aqueous humor, vitreous, retina, and lens ...
Ramakrishnan S +3 more
openaire +2 more sources
Transthyretin Tetramer Destabilization and Increased Mortality in the General Population
Importance: Transthyretin tetramer destabilization is the rate-limiting step in the development of transthyretin cardiac amyloidosis, an underrecognized contributor to mortality in older adults.Objective: To test the hypothesis that transthyretin ...
Tybjærg-Hansen, Anne +5 more
core +1 more source
Prognostic Impact of Serum Transthyretin and Sarcopenia on 3-Year Mortality and Respiratory-Related Hospitalizations in Idiopathic Pulmonary Fibrosis: A Prospective Cohort Study. [PDF]
Okada A +18 more
europepmc +1 more source
Effect of Transthyretin Stabilizer in Transthyretin Cardiac Amyloidosis
Toru, Kubo +3 more
openaire +2 more sources
Transthyretin and the transthyretin-related protein: A structural study
Transthyretin (TTR) is one of several proteins involved in amyloid disease in humans. Unknown conformational changes of the native state of TTR result in aggregation of TTR molecules into amyloid fibrils, which accumulate in extracellular tissues. This may result in different clinical symptoms, e.g.
openaire +1 more source
Ophthalmological Manifestations of Hereditary Amyloidosis due to Transthyretin: A Systematic Review. [PDF]
Fialho ML +5 more
europepmc +1 more source
Evaluation of serum neurofilament light chain, GFAP, and peripherin as biomarkers in hereditary transthyretin amyloidosis. [PDF]
Anan I +6 more
europepmc +1 more source
Serum Transthyretin as a Prognostic and Therapeutic Biomarker in Transthyretin Amyloid Cardiomyopathy Patients Treated with Tafamidis. [PDF]
Costantino J +7 more
europepmc +1 more source

