Transthyretin Tetramer Destabilization and Increased Mortality in the General Population
Importance: Transthyretin tetramer destabilization is the rate-limiting step in the development of transthyretin cardiac amyloidosis, an underrecognized contributor to mortality in older adults.Objective: To test the hypothesis that transthyretin ...
Tybjærg-Hansen, Anne +5 more
core +1 more source
Tafamidis: A First-in-Class Transthyretin Stabilizer for Transthyretin Amyloid Cardiomyopathy.
Objective: To review the pharmacology, efficacy, and safety of the selective transthyretin inhibitor tafamidis for transthyretin amyloid cardiomyopathy (ATTR-CM). Data Sources: A PubMed (1966 to October 2019) and ClinicalTrials.
Andrews, Ebony +5 more
core
Effect of Transthyretin Stabilizer in Transthyretin Cardiac Amyloidosis
Kubo, Toru +3 more
openaire +2 more sources
Transthyretin (prealbumin) in eye structures and variation of vitreous-transthyretin in diseases.
To evaluate the presence of transthyretin (TTR, prealbumin) a protein which binds retinol to retinol-binding protein in various ocular tissues and to study its quantitative changes in the vitreous humor in various diseases.Estimation of TTR was done by electrophoresis of 10 mg protein in each sample of tears, aqueous humor, vitreous, retina, and lens ...
Ramakrishnan S +3 more
openaire +2 more sources
Disease-Modifying Therapies for Transthyretin Amyloid Cardiomyopathy: Current Evidence and Emerging Strategies. [PDF]
Kachhadia MP +10 more
europepmc +1 more source
Polyneuropathy Assessment and Treatment Patterns in Patients with Hereditary Transthyretin Amyloidosis. [PDF]
Streicher N, Wubet H.
europepmc +1 more source
The biological interplay between aortic stenosis and transthyretin cardiac amyloidosis. [PDF]
Kitai T, Kim K, Rudzinski PN.
europepmc +1 more source
Case Report: Inotersen reintroduction after thrombocytopenia in hereditary transthyretin amyloidosis: a case series. [PDF]
Crespi CA +5 more
europepmc +1 more source

