Results 121 to 130 of about 10,856 (192)

Old disease, new twist

Journal of Hospital Medicine, Volume 21, Issue 11, Page 1305-1309, November 2026.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source

Nucleic Acid Therapeutics in Rare Disease: From Precision Medicine to Programmable Platforms

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Nucleic acid therapeutics (NATs), including antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), messenger RNA (mRNA) therapeutics and programmable editing technologies, are reshaping the therapeutic landscape for inherited metabolic and genetic disease.
Tomasz Z. Tomkiewicz, Siyamini Sivananthan, Paul Gissen, Haiyan Zhou   +3 more
wiley   +1 more source

Human transthyretin (TTR) complexed with ferulic acid and curcumin

, 2014
Human transthyretin (TTR) complexed with ferulic acid and ...
Ciccone, L., Stura, E. A.
core   +1 more source

Transthyretin distribution in the developing choroid plexus of the South American opossum (Monodelphis domestica)

, 1997
The distributions of transthyretin and albumin in the choroid plexus during brain development have been compared. The South American opossum was chosen because the young are born around the time of choroid plexus formation.
Norman Saunders (15436337), Dziegielewska, KM (15476936), Li, ZS (15477668)   +2 more
core  

Transthyretin Eiger 9M X-ray diffraction dataset

, 2018
Transthyretin X-ray diffraction dataset collected during commissioning of Eiger 9M detector on Proxima2A beamline, Synchrotron SOLEIL, France.
Martin Savko, Martin Savko (727851)
core   +1 more source

Experience of Hereditary Amyloidosis with Rare Variant in Ecuador: Case Reports

Medical Sciences
More than approximately 120 transthyretin mutations are known. Their clinical presentation is heterogeneous, as the course of disease onset depends on genetic variation and level of penetrance.
Diana Elizabeth Luzuriaga Carpio, Borys Roberto Abrigo Maldonado, Humberto Villacorta   +2 more
doaj   +1 more source

Specific Therapy in Transthyretin Amyloid Cardiomyopathy: Future Perspectives Beyond Tafamidis

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a relatively prevalent cause of morbidity and mortality. Over the recent years, development of disease-modifying treatments has enabled stabilization of the circulating transthyretin tetramer and ...
Porcari, Aldostefano, Sinagra, Gianfranco, Dore, Franca, Allegro, Valentina, Saro, Riccardo, Merlo, Marco   +5 more
core   +1 more source

The absence of transthyretin does not impair regulation of lipid and glucose metabolism

Increased levels of neuropeptide Y have been reported in transthyretin-null mice. This effect might be related to transthyretin ligands (retinol and thyroxine) since, through binding to nuclear receptors, they modulate the expression of genes that ...
Sousa, JC, Oliveira, HCF, Marques, F, Palha, JA, Marques, Fernanda, Oliveira, H. C. F., Sousa, João Carlos, Palha, Joana Almeida, Oliveira, P, Oliveira, P.   +9 more
core   +1 more source

Transthyretin [PDF]

, 2020
openaire   +1 more source

Early‐Onset Wild‐Type Transthyretin Amyloidosis Polyneuropathy

Muscle &Nerve, Volume 74, Issue 5, Page 1471-1475, November 2026.
Chafic Karam, Kaylee Baker, Sami Khella, Brian Drachman, Pranav Chandrashekar, MacLean Nasrallah, Shunsuke Koga, Janice Pieretti   +7 more
wiley   +1 more source