Results 111 to 120 of about 28,989 (238)
Palinacousis in amyloidosis: exploring the hallucinatory phenomenon in brain pathology—a case report
Background Hereditary transthyretin amyloidosis, caused by transthyretin gene mutations, progresses with systemic impact and often presents peripheral neuropathy.
João Martins-Correia, Luísa Sousa
doaj +1 more source
ABSTRACT Amyloidosis, characterized by the deposition of abnormal protein fibrils in organs, is classified as systemic or localized. Amyloid light chain (AL)‐type localized amyloidosis is uncommon, particularly when confined to the gastrointestinal tract.
Shunsuke Kojimahara +7 more
wiley +1 more source
See Article by Hanson et al > The future depends on what you do today. > > ―Mahatma Gandhi A biomarker is defined by the National Institutes of Health Biomarkers Definitions Working Group as “a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses ...
openaire +2 more sources
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni +5 more
wiley +1 more source
Transthyretin (TTR) is a transporter for thyroid hormone and retinol binding protein that has recently been reported to have proteolytic activity against certain substrates, including amidated neuropeptide Y (NPY).
Sukanya Tangthavewattana +2 more
doaj +1 more source
Three-dimensional structure of the Transthyretin-Retinol-Binding Protein Complex
Transthyretin (TTR), formerly called prealbumin, one of the transporters of the hormone thyroxine and retinol-binding protein (RBP), the specific carrier of vitamin A, forms, under physiological conditions, a macromolecular complex that prevents ...
MONACO, Ugo Luigi
core
Concurrent Tongue and Cervical Lymph Node Amyloidosis Without Systemic Disease
ABSTRACT Amyloidosis of the head and neck is often associated with systemic involvement. However, this report describes a rare presentation of localized amyloidosis involving both the tongue and cervical lymph nodes in a patient without systemic disease.
Chelsea O. Onyeji +2 more
wiley +1 more source
The Effect of Protein Tagging on Aggregation and Phase Separation
ABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Harunobu Saito, Kenji Sugase
wiley +1 more source
EV‐SPEC: Decoding the Spatial Proteomic Signature of the Extracellular Vesicle Corona
This study introduces ‘EV‑SPEC’, a spatial proteomics method using TurboID fused to the transmembrane protein CD63 to map the protein corona of extracellular vesicles (EVs) without physical isolation. We show that EV‐SPEC identifies the protein‐protein interaction footprint of serum proteins, similar to those typically found on synthetic nanoparticles,
Camille Menaceur Vandenbroucke +2 more
wiley +1 more source
New Medications in the Treatment of Hereditary Transthyretin Amyloidosis
Hereditary transthyretin amyloidosis is an inherited disorder that results in the gradual progressive deposit of abnormal protein called amyloid in the body’s organs and tissues.
Scot Walker
core +1 more source

